METHOD OF SYNTHESIS OF DISUBSTITUTED PIPERIDINE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS
The (3R,S)- or (3R)- form of a compound of the formula:- or a pharmaceutically acceptable salt thereof, wherein R is a group of the formula:- where each Y, which may be the same or different, is selected from the substituents hydrogen, halo and C1-C4 alkyl: X is -(CH2)2-, -CH=CH-, -CH2-S-, -CH2-O-,...
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creator | DEVID ELKER PITER EDVARD KROSS ROBERT MAJKL VOLLIS |
description | The (3R,S)- or (3R)- form of a compound of the formula:- or a pharmaceutically acceptable salt thereof, wherein R is a group of the formula:- where each Y, which may be the same or different, is selected from the substituents hydrogen, halo and C1-C4 alkyl: X is -(CH2)2-, -CH=CH-, -CH2-S-, -CH2-O-, -S- or -O-; and R is a group of the formula:- wherein R , R , R and R are certain specified substituents. The compounds are useful in the treatment of diseases associated with altered motility and/or tone of smooth muscle. |
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The compounds are useful in the treatment of diseases associated with altered motility and/or tone of smooth muscle.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1993</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFi0EKwjAQRbtxIeoZnAsIShd2O02mZCBtQzIpdFVKSVeihXp_rODe1X8P3t9nc01iWg1tBaFvxFDg8BXNIZZBWKKQBseOPGtuCPQGHQp3tHUetgd7cAZ9jYqisEJre0ClyAmWliCglXDMdvP4WNPpt4fsXJEoc0nLa0jrMk7pmd6Dj7ciL_LrXeX_iw82UDT2</recordid><startdate>19930830</startdate><enddate>19930830</enddate><creator>DEVID ELKER</creator><creator>PITER EDVARD KROSS</creator><creator>ROBERT MAJKL VOLLIS</creator><scope>EVB</scope></search><sort><creationdate>19930830</creationdate><title>METHOD OF SYNTHESIS OF DISUBSTITUTED PIPERIDINE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS</title><author>DEVID ELKER ; PITER EDVARD KROSS ; ROBERT MAJKL VOLLIS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU1838307C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1993</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DEVID ELKER</creatorcontrib><creatorcontrib>PITER EDVARD KROSS</creatorcontrib><creatorcontrib>ROBERT MAJKL VOLLIS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DEVID ELKER</au><au>PITER EDVARD KROSS</au><au>ROBERT MAJKL VOLLIS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF SYNTHESIS OF DISUBSTITUTED PIPERIDINE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS</title><date>1993-08-30</date><risdate>1993</risdate><abstract>The (3R,S)- or (3R)- form of a compound of the formula:- or a pharmaceutically acceptable salt thereof, wherein R is a group of the formula:- where each Y, which may be the same or different, is selected from the substituents hydrogen, halo and C1-C4 alkyl: X is -(CH2)2-, -CH=CH-, -CH2-S-, -CH2-O-, -S- or -O-; and R is a group of the formula:- wherein R , R , R and R are certain specified substituents. The compounds are useful in the treatment of diseases associated with altered motility and/or tone of smooth muscle.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | METHOD OF SYNTHESIS OF DISUBSTITUTED PIPERIDINE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS |
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