MULTISPECIFIC ANTIBODIES FACILITATING SELECTIVE LIGHT CHAIN PAIRING

Provided herein are multispecific antibodies, e.g. bispecific antibodies, which are modified such that the desired chain pairing takes place and/or can be selected for. Specifically, this is achieved by using different dimerization domains for light chain pairing. Also disclosed herein are nucleic a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	LEUSCHNER, WULF-DIRK, RAO, ERCOLE, SPINDLER, NADJA, LANGER, THOMAS, LANGE, CHRISTIAN, BEIL, CHRISTIAN, KROLL, KATJA, FOCKEN, INGO
Format:	Patent
Sprache:	eng ; srp
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
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