PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER
The present invention provides MDM2 inhibitor compounds of Formula IE,which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.
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| creator | JIAO, XIANJUN WANG, XIAODONG DEIGNAN, JEFFREY FISHER, BENJAMIN EKSTEROWICZ, JOHN MCINTOSH, JOEL ZHU, JIANG FU, JIASHENG GUSTIN, DARIN JAMES LI, ZHIHONG JOHNSON, MICHAEL BECK, HILARY PLACE MCGEE, LAWRENCE R MCMINN, DUSTIN LAI, SUJEN REW, YOSUP HUANG, XIN SUN, DAQING WANG, YINGCAI HEATH, JULIE ANNE MEDINA, JULIO CESAR BARTBERGER, MICHAEL DAVID GONZALEZ LOPEZ DE TURISO, FELIX LIU, JIWEN CONNORS, RICHARD VICTOR KOPECKY, DAVID JOHN MA, ZHIHUA DUQUETTE, JASON A FU, ZICE MIHALIC, JEFFREY THOMAS YAN, XUELEI FOX, BRIAN MATTHEW LOW, JONATHAN DANTE CHEN, XIAOQI KAYSER, FRANK GRIBBLE, JR., MICHAEL WILLIAM OLSON, STEVEN HOWARD ROVETO, PHILIP MARLEY GONZALEZ BUENROSTRO, ANA LUCAS, BRIAN STUART YU, MING LI, YIHONG |
| description | The present invention provides MDM2 inhibitor compounds of Formula IE,which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor. |
| format | Patent |
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The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER |
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