PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII

The present invention provides compounds of formula (I)wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising...

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Hauptverfasser: HU, TAISHAN, BEIGNET, JULIEN, STOLL, THEODOR, ALANINE, ALEXANDER, FASCHING, BERNHARD, THOMAS, HELMUT, KROLL, CARSTEN, SCHAEUBLIN, ADRIAN, MACDONALD, DWIGHT, WAHHAB, AMAL, HILPERT, HANS, KOLCZEWSKI, SABINE, BLEICHER, KONRAD, JACKSON, STEPHEN, ZAMPALONI, CLAUDIA, SHEN, HONG
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creator HU, TAISHAN
BEIGNET, JULIEN
STOLL, THEODOR
ALANINE, ALEXANDER
FASCHING, BERNHARD
THOMAS, HELMUT
KROLL, CARSTEN
SCHAEUBLIN, ADRIAN
MACDONALD, DWIGHT
WAHHAB, AMAL
HILPERT, HANS
KOLCZEWSKI, SABINE
BLEICHER, KONRAD
JACKSON, STEPHEN
ZAMPALONI, CLAUDIA
SHEN, HONG
description The present invention provides compounds of formula (I)wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baumannii.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PEPTIDE MACROCYCLES AGAINST ACINETOBACTER BAUMANNII
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