BENZIMIDAZOLE DERIVATIVES

The present invention relates to a compound of the Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3A, R3B, R4, R5, X, m, and n are as defined herein. Such novel benzamidazole derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This...

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Hauptverfasser: JONES, CHRISTOPHER, SCOTT, MUNCHHOF, MICHAEL, JOHN, LA GRECA, SUSAN, REITER, LAWRENCE, ALAN, LI, QIFANG
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creator JONES, CHRISTOPHER, SCOTT
MUNCHHOF, MICHAEL, JOHN
LA GRECA, SUSAN
REITER, LAWRENCE, ALAN
LI, QIFANG
description The present invention relates to a compound of the Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3A, R3B, R4, R5, X, m, and n are as defined herein. Such novel benzamidazole derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BENZIMIDAZOLE DERIVATIVES
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