ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME
Jedinjenje formule (I):gde je:R1 alkil, cikloalkil, ketocikloalkil, heterociklil, aril ili heteroaril, gde je svako po potrebi mono-, di-, ili tri-supstituisano nezavisno sa alkil, alkoksi, halogen, cijano, nitro, trifluoroalkil, amino, alkilamino, dialkilamino, acil, aril, heteroaril, heterociklil,...
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| creator | MA, GIL JIMENEZ, HERMOGENES, N WHITE, ANDREW, D DOLLER, DARIO GUO, MAOJUN LI, GUIYING GRENON, MICHEL |
| description | Jedinjenje formule (I):gde je:R1 alkil, cikloalkil, ketocikloalkil, heterociklil, aril ili heteroaril, gde je svako po potrebi mono-, di-, ili tri-supstituisano nezavisno sa alkil, alkoksi, halogen, cijano, nitro, trifluoroalkil, amino, alkilamino, dialkilamino, acil, aril, heteroaril, heterociklil, heterociklil-R3, -NHR3, -N(alkil)R3, -C(O)NHR3, -C(O)N(alkil)R3, -NHC(O)R3, -N(alkil)C(O)R3, -OH ili -OR3, iR2 je C2-C6 alkil, cikloalkil, ketocikloalkil, heterociklil, aril ili heteroaril, gde je svako po potrebi mono-, di-, ili tri-supstituisano nezavisno sa alkil, alkoksi, halogen, cijano, nitro, trifluoroalkil, amino, alkilamino, dialkilamino, acil, aril, heteroaril, heterociklil, heterociklil-R3, -NHR3, -N(alkil)R3, -C(O)NHR3, -C(O)N(alkil)R3, - NHC(O)R3, -N(alkil)C(O)R3, -OH ili -OR3, gde je:R3 C1-C6 alkil ili C1-C6 cikloalkil, koji je po potrebi supstituisan sa halogen, C1-C3 alkoksi, OH, -CN, -NH2, -NH(C1-C3alkil), -N(C1-C3alkil)2, C1-3alkilheterociklil, C1-C3alkilkarbamat, -C(O)NH(C1-C3alkil), -C(O)N(C1-C3alkil)2, -NHC(O)- C1-C3alkil, -N(C1-C3alkil)-C(O)- C1-C3alkil, OH, ili -O- C1-C6alkil;pod uslovom da jedinjenje formule (I) nije:N, N'-(1, 3-adamantilen)bis(3-metoksi-benzamid);N, N'-(1, 3-adamantilen)bis(4-etoksi-benzamid);N, N'-(1, 3-adamantilen)bis(4-metoksi-benzamid);N, N'-(1, 3-adamantilen)bis(3, 4, 5-trimetoksibenzamid);N, N'-(1, 3-adamantilen)bis(2-jodo-benzamid);N, N'-(1, 3-adamantilen)bis-benzamid;N, N'-(1, 3-adamantilen)bis(3-nitrobenzamid); iN, N'-(1, 3-adamantilen)bis- (3-piridinkarboksamid);ili njegova farmaceutski prihvatljiva so.Prijava sadrži još 13 patentnih zahteva.
The present invention provides adamantyl-diamide derivatives of formula (I): wherein R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and methods using the same. |
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| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RS53019B</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RS53019B</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RS53019B3</originalsourceid><addsrcrecordid>eNrjZNBzdHH0dfQLifRRcPF09PV0cVVwcQ3yDHMM8QxzDVZw9HNRCA0GMvzdFIIdfV15GFjTEnOKU3mhNDeDrJtriLOHbmpBfnxqcUFicmpeakl8ULCpsYGhpZMxIXkAr0Aj9w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME</title><source>esp@cenet</source><creator>MA, GIL ; JIMENEZ, HERMOGENES, N ; WHITE, ANDREW, D ; DOLLER, DARIO ; GUO, MAOJUN ; LI, GUIYING ; GRENON, MICHEL</creator><creatorcontrib>MA, GIL ; JIMENEZ, HERMOGENES, N ; WHITE, ANDREW, D ; DOLLER, DARIO ; GUO, MAOJUN ; LI, GUIYING ; GRENON, MICHEL</creatorcontrib><description>Jedinjenje formule (I):gde je:R1 alkil, cikloalkil, ketocikloalkil, heterociklil, aril ili heteroaril, gde je svako po potrebi mono-, di-, ili tri-supstituisano nezavisno sa alkil, alkoksi, halogen, cijano, nitro, trifluoroalkil, amino, alkilamino, dialkilamino, acil, aril, heteroaril, heterociklil, heterociklil-R3, -NHR3, -N(alkil)R3, -C(O)NHR3, -C(O)N(alkil)R3, -NHC(O)R3, -N(alkil)C(O)R3, -OH ili -OR3, iR2 je C2-C6 alkil, cikloalkil, ketocikloalkil, heterociklil, aril ili heteroaril, gde je svako po potrebi mono-, di-, ili tri-supstituisano nezavisno sa alkil, alkoksi, halogen, cijano, nitro, trifluoroalkil, amino, alkilamino, dialkilamino, acil, aril, heteroaril, heterociklil, heterociklil-R3, -NHR3, -N(alkil)R3, -C(O)NHR3, -C(O)N(alkil)R3, - NHC(O)R3, -N(alkil)C(O)R3, -OH ili -OR3, gde je:R3 C1-C6 alkil ili C1-C6 cikloalkil, koji je po potrebi supstituisan sa halogen, C1-C3 alkoksi, OH, -CN, -NH2, -NH(C1-C3alkil), -N(C1-C3alkil)2, C1-3alkilheterociklil, C1-C3alkilkarbamat, -C(O)NH(C1-C3alkil), -C(O)N(C1-C3alkil)2, -NHC(O)- C1-C3alkil, -N(C1-C3alkil)-C(O)- C1-C3alkil, OH, ili -O- C1-C6alkil;pod uslovom da jedinjenje formule (I) nije:N, N'-(1, 3-adamantilen)bis(3-metoksi-benzamid);N, N'-(1, 3-adamantilen)bis(4-etoksi-benzamid);N, N'-(1, 3-adamantilen)bis(4-metoksi-benzamid);N, N'-(1, 3-adamantilen)bis(3, 4, 5-trimetoksibenzamid);N, N'-(1, 3-adamantilen)bis(2-jodo-benzamid);N, N'-(1, 3-adamantilen)bis-benzamid;N, N'-(1, 3-adamantilen)bis(3-nitrobenzamid); iN, N'-(1, 3-adamantilen)bis- (3-piridinkarboksamid);ili njegova farmaceutski prihvatljiva so.Prijava sadrži još 13 patentnih zahteva.
The present invention provides adamantyl-diamide derivatives of formula (I): wherein R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and methods using the same.</description><language>eng ; srp</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140430&DB=EPODOC&CC=RS&NR=53019B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140430&DB=EPODOC&CC=RS&NR=53019B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MA, GIL</creatorcontrib><creatorcontrib>JIMENEZ, HERMOGENES, N</creatorcontrib><creatorcontrib>WHITE, ANDREW, D</creatorcontrib><creatorcontrib>DOLLER, DARIO</creatorcontrib><creatorcontrib>GUO, MAOJUN</creatorcontrib><creatorcontrib>LI, GUIYING</creatorcontrib><creatorcontrib>GRENON, MICHEL</creatorcontrib><title>ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME</title><description>Jedinjenje formule (I):gde je:R1 alkil, cikloalkil, ketocikloalkil, heterociklil, aril ili heteroaril, gde je svako po potrebi mono-, di-, ili tri-supstituisano nezavisno sa alkil, alkoksi, halogen, cijano, nitro, trifluoroalkil, amino, alkilamino, dialkilamino, acil, aril, heteroaril, heterociklil, heterociklil-R3, -NHR3, -N(alkil)R3, -C(O)NHR3, -C(O)N(alkil)R3, -NHC(O)R3, -N(alkil)C(O)R3, -OH ili -OR3, iR2 je C2-C6 alkil, cikloalkil, ketocikloalkil, heterociklil, aril ili heteroaril, gde je svako po potrebi mono-, di-, ili tri-supstituisano nezavisno sa alkil, alkoksi, halogen, cijano, nitro, trifluoroalkil, amino, alkilamino, dialkilamino, acil, aril, heteroaril, heterociklil, heterociklil-R3, -NHR3, -N(alkil)R3, -C(O)NHR3, -C(O)N(alkil)R3, - NHC(O)R3, -N(alkil)C(O)R3, -OH ili -OR3, gde je:R3 C1-C6 alkil ili C1-C6 cikloalkil, koji je po potrebi supstituisan sa halogen, C1-C3 alkoksi, OH, -CN, -NH2, -NH(C1-C3alkil), -N(C1-C3alkil)2, C1-3alkilheterociklil, C1-C3alkilkarbamat, -C(O)NH(C1-C3alkil), -C(O)N(C1-C3alkil)2, -NHC(O)- C1-C3alkil, -N(C1-C3alkil)-C(O)- C1-C3alkil, OH, ili -O- C1-C6alkil;pod uslovom da jedinjenje formule (I) nije:N, N'-(1, 3-adamantilen)bis(3-metoksi-benzamid);N, N'-(1, 3-adamantilen)bis(4-etoksi-benzamid);N, N'-(1, 3-adamantilen)bis(4-metoksi-benzamid);N, N'-(1, 3-adamantilen)bis(3, 4, 5-trimetoksibenzamid);N, N'-(1, 3-adamantilen)bis(2-jodo-benzamid);N, N'-(1, 3-adamantilen)bis-benzamid;N, N'-(1, 3-adamantilen)bis(3-nitrobenzamid); iN, N'-(1, 3-adamantilen)bis- (3-piridinkarboksamid);ili njegova farmaceutski prihvatljiva so.Prijava sadrži još 13 patentnih zahteva.
The present invention provides adamantyl-diamide derivatives of formula (I): wherein R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and methods using the same.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNBzdHH0dfQLifRRcPF09PV0cVVwcQ3yDHMM8QxzDVZw9HNRCA0GMvzdFIIdfV15GFjTEnOKU3mhNDeDrJtriLOHbmpBfnxqcUFicmpeakl8ULCpsYGhpZMxIXkAr0Aj9w</recordid><startdate>20140430</startdate><enddate>20140430</enddate><creator>MA, GIL</creator><creator>JIMENEZ, HERMOGENES, N</creator><creator>WHITE, ANDREW, D</creator><creator>DOLLER, DARIO</creator><creator>GUO, MAOJUN</creator><creator>LI, GUIYING</creator><creator>GRENON, MICHEL</creator><scope>EVB</scope></search><sort><creationdate>20140430</creationdate><title>ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME</title><author>MA, GIL ; JIMENEZ, HERMOGENES, N ; WHITE, ANDREW, D ; DOLLER, DARIO ; GUO, MAOJUN ; LI, GUIYING ; GRENON, MICHEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RS53019B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; srp</language><creationdate>2014</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MA, GIL</creatorcontrib><creatorcontrib>JIMENEZ, HERMOGENES, N</creatorcontrib><creatorcontrib>WHITE, ANDREW, D</creatorcontrib><creatorcontrib>DOLLER, DARIO</creatorcontrib><creatorcontrib>GUO, MAOJUN</creatorcontrib><creatorcontrib>LI, GUIYING</creatorcontrib><creatorcontrib>GRENON, MICHEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MA, GIL</au><au>JIMENEZ, HERMOGENES, N</au><au>WHITE, ANDREW, D</au><au>DOLLER, DARIO</au><au>GUO, MAOJUN</au><au>LI, GUIYING</au><au>GRENON, MICHEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME</title><date>2014-04-30</date><risdate>2014</risdate><abstract>Jedinjenje formule (I):gde je:R1 alkil, cikloalkil, ketocikloalkil, heterociklil, aril ili heteroaril, gde je svako po potrebi mono-, di-, ili tri-supstituisano nezavisno sa alkil, alkoksi, halogen, cijano, nitro, trifluoroalkil, amino, alkilamino, dialkilamino, acil, aril, heteroaril, heterociklil, heterociklil-R3, -NHR3, -N(alkil)R3, -C(O)NHR3, -C(O)N(alkil)R3, -NHC(O)R3, -N(alkil)C(O)R3, -OH ili -OR3, iR2 je C2-C6 alkil, cikloalkil, ketocikloalkil, heterociklil, aril ili heteroaril, gde je svako po potrebi mono-, di-, ili tri-supstituisano nezavisno sa alkil, alkoksi, halogen, cijano, nitro, trifluoroalkil, amino, alkilamino, dialkilamino, acil, aril, heteroaril, heterociklil, heterociklil-R3, -NHR3, -N(alkil)R3, -C(O)NHR3, -C(O)N(alkil)R3, - NHC(O)R3, -N(alkil)C(O)R3, -OH ili -OR3, gde je:R3 C1-C6 alkil ili C1-C6 cikloalkil, koji je po potrebi supstituisan sa halogen, C1-C3 alkoksi, OH, -CN, -NH2, -NH(C1-C3alkil), -N(C1-C3alkil)2, C1-3alkilheterociklil, C1-C3alkilkarbamat, -C(O)NH(C1-C3alkil), -C(O)N(C1-C3alkil)2, -NHC(O)- C1-C3alkil, -N(C1-C3alkil)-C(O)- C1-C3alkil, OH, ili -O- C1-C6alkil;pod uslovom da jedinjenje formule (I) nije:N, N'-(1, 3-adamantilen)bis(3-metoksi-benzamid);N, N'-(1, 3-adamantilen)bis(4-etoksi-benzamid);N, N'-(1, 3-adamantilen)bis(4-metoksi-benzamid);N, N'-(1, 3-adamantilen)bis(3, 4, 5-trimetoksibenzamid);N, N'-(1, 3-adamantilen)bis(2-jodo-benzamid);N, N'-(1, 3-adamantilen)bis-benzamid;N, N'-(1, 3-adamantilen)bis(3-nitrobenzamid); iN, N'-(1, 3-adamantilen)bis- (3-piridinkarboksamid);ili njegova farmaceutski prihvatljiva so.Prijava sadrži još 13 patentnih zahteva.
The present invention provides adamantyl-diamide derivatives of formula (I): wherein R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and methods using the same.</abstract><oa>free_for_read</oa></addata></record> |
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| title | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME |
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