3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES AS OPOID RECEPTOR ANTAGONISTS
The subject invention provides a compound of the formula (I), wherein X, Q, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined. Compounds of formula (I) have activity as opioid receptor antagonists. The subject invention furthermore provides for pharmaceutical compositions and therapeutic...
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| creator | HECK STEVEN DONALD LIRAS SPIROS MCHARDY STANTON FURST |
| description | The subject invention provides a compound of the formula (I), wherein X, Q, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined. Compounds of formula (I) have activity as opioid receptor antagonists. The subject invention furthermore provides for pharmaceutical compositions and therapeutic methods comprising compounds of formula (I).
Dati pronalazak daje jedinjenja formule (I), gde su X, Q, n, R1, R2, R3, R4, R5, R6, R7, R8, R9 i R10 kao što je odredjeno. Jedinjenja formule (I) deluju kao antagonisti opijatnih receptora. Dati pronalazak dalje daje farmaceutske kompozicije i terapeutske postupke koji sadrže jedinjenja formule (I). |
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Dati pronalazak daje jedinjenja formule (I), gde su X, Q, n, R1, R2, R3, R4, R5, R6, R7, R8, R9 i R10 kao što je odredjeno. Jedinjenja formule (I) deluju kao antagonisti opijatnih receptora. Dati pronalazak dalje daje farmaceutske kompozicije i terapeutske postupke koji sadrže jedinjenja formule (I).</description><language>eng ; srp</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2007</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070205&DB=EPODOC&CC=RS&NR=25104A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070205&DB=EPODOC&CC=RS&NR=25104A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HECK STEVEN DONALD</creatorcontrib><creatorcontrib>LIRAS SPIROS</creatorcontrib><creatorcontrib>MCHARDY STANTON FURST</creatorcontrib><title>3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES AS OPOID RECEPTOR ANTAGONISTS</title><description>The subject invention provides a compound of the formula (I), wherein X, Q, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined. Compounds of formula (I) have activity as opioid receptor antagonists. The subject invention furthermore provides for pharmaceutical compositions and therapeutic methods comprising compounds of formula (I).
Dati pronalazak daje jedinjenja formule (I), gde su X, Q, n, R1, R2, R3, R4, R5, R6, R7, R8, R9 i R10 kao što je odredjeno. Jedinjenja formule (I) deluju kao antagonisti opijatnih receptora. Dati pronalazak dalje daje farmaceutske kompozicije i terapeutske postupke koji sadrže jedinjenja formule (I).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2007</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHA21nWMcnTydI509vHXMNYz1DPQ9HCNcPRzVXBxDfIMcwzxDHMNVnAMVvAP8Pd0UQhydXYNCPEPUnD0C3F09_fzDA4J5mFgTUvMKU7lhdLcDLJuriHOHrqpBfnxqcUFicmpeakl8UHBRqaGBiaOxoTkAZ3lKYE</recordid><startdate>20070205</startdate><enddate>20070205</enddate><creator>HECK STEVEN DONALD</creator><creator>LIRAS SPIROS</creator><creator>MCHARDY STANTON FURST</creator><scope>EVB</scope></search><sort><creationdate>20070205</creationdate><title>3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES AS OPOID RECEPTOR ANTAGONISTS</title><author>HECK STEVEN DONALD ; LIRAS SPIROS ; MCHARDY STANTON FURST</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RS25104A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; srp</language><creationdate>2007</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HECK STEVEN DONALD</creatorcontrib><creatorcontrib>LIRAS SPIROS</creatorcontrib><creatorcontrib>MCHARDY STANTON FURST</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HECK STEVEN DONALD</au><au>LIRAS SPIROS</au><au>MCHARDY STANTON FURST</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES AS OPOID RECEPTOR ANTAGONISTS</title><date>2007-02-05</date><risdate>2007</risdate><abstract>The subject invention provides a compound of the formula (I), wherein X, Q, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined. Compounds of formula (I) have activity as opioid receptor antagonists. The subject invention furthermore provides for pharmaceutical compositions and therapeutic methods comprising compounds of formula (I).
Dati pronalazak daje jedinjenja formule (I), gde su X, Q, n, R1, R2, R3, R4, R5, R6, R7, R8, R9 i R10 kao što je odredjeno. Jedinjenja formule (I) deluju kao antagonisti opijatnih receptora. Dati pronalazak dalje daje farmaceutske kompozicije i terapeutske postupke koji sadrže jedinjenja formule (I).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES AS OPOID RECEPTOR ANTAGONISTS |
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