PRODUCTION AND USE OF MODERN OVOTRANSFERRIN ()
The invention relates to a method for producing the ovotransferrin OTF-M specific for a target antigen, with applications in medicine. According to the invention, the method consists in the immunisation of the laying hens with an antigen consisting of a mixture of bacterial strains resistant to anti...
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| creator | PĂTRAŞCU IONEL-VICTOR CHIURCIU VIORICA CHIURCIU CONSTANTIN OPORANU MARIANA TOPILESCU GEORGIANA |
| description | The invention relates to a method for producing the ovotransferrin OTF-M specific for a target antigen, with applications in medicine. According to the invention, the method consists in the immunisation of the laying hens with an antigen consisting of a mixture of bacterial strains resistant to antibiotics, isolation of the white from the eggs produced by the immunised hens, followed by diluting it in a ratio of 1:1 with deionized water, adjusting the pH to 5, settling in two stages with ammonium sulphate and citric acid, followed by dialysis and lyophilisation.
Invenţia se referă la o metodă de producere a ovotransferinei specifice OTF-M pentru un antigen ţintă cu aplicaţii în medicină. Metoda conform invenţiei constă în imunizarea găinilor ouătoare cu un antigen format dintr-un amestec de tulpini bacteriene rezistente la antibiotice, izolarea albuşului din ouăle care provin de la găinile imunizate, diluarea acestuia în raport de 1:1 cu apă deionizată, ajustareaH la 5, precipitarea în două etape cu sulfat de amoniu şi acid citric, urmată de dializă şi liofilizare. |
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Invenţia se referă la o metodă de producere a ovotransferinei specifice OTF-M pentru un antigen ţintă cu aplicaţii în medicină. Metoda conform invenţiei constă în imunizarea găinilor ouătoare cu un antigen format dintr-un amestec de tulpini bacteriene rezistente la antibiotice, izolarea albuşului din ouăle care provin de la găinile imunizate, diluarea acestuia în raport de 1:1 cu apă deionizată, ajustareaH la 5, precipitarea în două etape cu sulfat de amoniu şi acid citric, urmată de dializă şi liofilizare.</description><language>eng ; rum</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170630&DB=EPODOC&CC=RO&NR=130063A8$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170630&DB=EPODOC&CC=RO&NR=130063A8$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PĂTRAŞCU IONEL-VICTOR</creatorcontrib><creatorcontrib>CHIURCIU VIORICA</creatorcontrib><creatorcontrib>CHIURCIU CONSTANTIN</creatorcontrib><creatorcontrib>OPORANU MARIANA</creatorcontrib><creatorcontrib>TOPILESCU GEORGIANA</creatorcontrib><title>PRODUCTION AND USE OF MODERN OVOTRANSFERRIN ()</title><description>The invention relates to a method for producing the ovotransferrin OTF-M specific for a target antigen, with applications in medicine. According to the invention, the method consists in the immunisation of the laying hens with an antigen consisting of a mixture of bacterial strains resistant to antibiotics, isolation of the white from the eggs produced by the immunised hens, followed by diluting it in a ratio of 1:1 with deionized water, adjusting the pH to 5, settling in two stages with ammonium sulphate and citric acid, followed by dialysis and lyophilisation.
Invenţia se referă la o metodă de producere a ovotransferinei specifice OTF-M pentru un antigen ţintă cu aplicaţii în medicină. Metoda conform invenţiei constă în imunizarea găinilor ouătoare cu un antigen format dintr-un amestec de tulpini bacteriene rezistente la antibiotice, izolarea albuşului din ouăle care provin de la găinile imunizate, diluarea acestuia în raport de 1:1 cu apă deionizată, ajustareaH la 5, precipitarea în două etape cu sulfat de amoniu şi acid citric, urmată de dializă şi liofilizare.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNALCPJ3CXUO8fT3U3D0c1EIDXZV8HdT8PV3cQ3yU_AP8w8JcvQLdnMNCvL0U9DQ5GFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8UH-hsYGBmbGjhbGhFUAAEaVJM8</recordid><startdate>20170630</startdate><enddate>20170630</enddate><creator>PĂTRAŞCU IONEL-VICTOR</creator><creator>CHIURCIU VIORICA</creator><creator>CHIURCIU CONSTANTIN</creator><creator>OPORANU MARIANA</creator><creator>TOPILESCU GEORGIANA</creator><scope>EVB</scope></search><sort><creationdate>20170630</creationdate><title>PRODUCTION AND USE OF MODERN OVOTRANSFERRIN ()</title><author>PĂTRAŞCU IONEL-VICTOR ; CHIURCIU VIORICA ; CHIURCIU CONSTANTIN ; OPORANU MARIANA ; TOPILESCU GEORGIANA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RO130063A83</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rum</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><toplevel>online_resources</toplevel><creatorcontrib>PĂTRAŞCU IONEL-VICTOR</creatorcontrib><creatorcontrib>CHIURCIU VIORICA</creatorcontrib><creatorcontrib>CHIURCIU CONSTANTIN</creatorcontrib><creatorcontrib>OPORANU MARIANA</creatorcontrib><creatorcontrib>TOPILESCU GEORGIANA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PĂTRAŞCU IONEL-VICTOR</au><au>CHIURCIU VIORICA</au><au>CHIURCIU CONSTANTIN</au><au>OPORANU MARIANA</au><au>TOPILESCU GEORGIANA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PRODUCTION AND USE OF MODERN OVOTRANSFERRIN ()</title><date>2017-06-30</date><risdate>2017</risdate><abstract>The invention relates to a method for producing the ovotransferrin OTF-M specific for a target antigen, with applications in medicine. According to the invention, the method consists in the immunisation of the laying hens with an antigen consisting of a mixture of bacterial strains resistant to antibiotics, isolation of the white from the eggs produced by the immunised hens, followed by diluting it in a ratio of 1:1 with deionized water, adjusting the pH to 5, settling in two stages with ammonium sulphate and citric acid, followed by dialysis and lyophilisation.
Invenţia se referă la o metodă de producere a ovotransferinei specifice OTF-M pentru un antigen ţintă cu aplicaţii în medicină. Metoda conform invenţiei constă în imunizarea găinilor ouătoare cu un antigen format dintr-un amestec de tulpini bacteriene rezistente la antibiotice, izolarea albuşului din ouăle care provin de la găinile imunizate, diluarea acestuia în raport de 1:1 cu apă deionizată, ajustareaH la 5, precipitarea în două etape cu sulfat de amoniu şi acid citric, urmată de dializă şi liofilizare.</abstract><oa>free_for_read</oa></addata></record> |
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| title | PRODUCTION AND USE OF MODERN OVOTRANSFERRIN () |
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