PROCESSO PARA A PREPARACAO DE DERIVADOS DE VITAMINA D HOMOLOGOS DE CADEIAS LATERAIS E DE COMPOSICOES FARMACEUTICAS QUE OS CONTEM
The description relates to novel side-chain-homologous vitamin D derivatives of formula (I), in which R , R , R , R , R and R have the significance given in the description, B and D are either a hydrogen atom or together a second bond (E-configuration double bond) and either A is a direct bond betwe...
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| creator | MATTHIAS BRAUTIGAM PETRA RACH GUNFER NEEF KATICA SCHWARZ RUTH THIEROFF-EKERDT ANDREAS STEINMEYER GERALD KIRSCH |
| description | The description relates to novel side-chain-homologous vitamin D derivatives of formula (I), in which R , R , R , R , R and R have the significance given in the description, B and D are either a hydrogen atom or together a second bond (E-configuration double bond) and either A is a direct bond between the carbon atoms 20 and 22 and X is an alkyloxy radical -(CH2)nO- with n = 1 to 3 or A is a methylene bridge (-CH2-) between the carbon atoms 20 and 22 and X is an alkylene radical -(CH2)n- or an alkylenoxy radical -(CH2)nO- with n = 1 to 3, or if A is a direct bond and B and D together are a second bond, (a) is one of the radicals (b) , -(CH2)2-= or -(CH2)2-=, and a process for their production, pharmaceutical preparations containing this compound and its use in making medicaments. The new compounds have proliferation-inhibiting and cell-differentiating effects. |
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The new compounds have proliferation-inhibiting and cell-differentiating effects.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESSO PARA A PREPARACAO DE DERIVADOS DE VITAMINA D HOMOLOGOS DE CADEIAS LATERAIS E DE COMPOSICOES FARMACEUTICAS QUE OS CONTEM |
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