BENZOCICLOALCENOS SUBSTITUIDOS E SUA UTILIZACAO COMO SUBSTANCIAS COM EFEITO ANALGESICO

Aminomethyl substituted heterocyclic benzocycloalkene derivatives (I) are new. Aminomethyl substituted heterocyclic benzocycloalkene derivatives of formula (I) and their salts are new: R = OH; 1-6C alkoxy; or 3-7C cycloalkyloxy; R = 1-6C alkyl; R = 1-6C alkyl; aryl-1-2C alkyl; heterocyclyl-1-2C alky...

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Hauptverfasser: OSWALD ZIMMER, WERNER ENGLBERGER, WOLFGANG STRASSBURGER, DR, CLAUDIA PUTZ, BABETTE-YVONNE KOGEL
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creator OSWALD ZIMMER
WERNER ENGLBERGER
WOLFGANG STRASSBURGER, DR
CLAUDIA PUTZ
BABETTE-YVONNE KOGEL
description Aminomethyl substituted heterocyclic benzocycloalkene derivatives (I) are new. Aminomethyl substituted heterocyclic benzocycloalkene derivatives of formula (I) and their salts are new: R = OH; 1-6C alkoxy; or 3-7C cycloalkyloxy; R = 1-6C alkyl; R = 1-6C alkyl; aryl-1-2C alkyl; heterocyclyl-1-2C alkyl; -CH2-CH=C(R )2; or 3-7C cycloalkyl-methyl; R , R = H; Cl; F; CF3; 1-6C alkyl; OH; 1-6C alkoxy; 3-7C cycloalkyloxy; alpha , beta or beta , gamma -O-(CH2)o-O-; -(CH2)n-aryl; heterocyclyl; -O-(CH2)n-aryl; or alpha , beta - or beta , gamma -benzo optionally mono- or disubstituted by F, Cl, CF3, OH, 1-6C alkyl, 1-6C alkoxy or -CON(R R ); R = H or 1-6C alkyl; R = H; 1-6C alkyl; -(CH2)naryl; or CH2-3-7C cycloalkyl; or R + R = -(CH2)m or -(CH2)2-O-(CH2)2-; X = O; S; SO; or SO2; Y = -(CH2)0; -CH2-C(CH3)2-; or -C(CH3)2-; n = 0-2; m = 5-7; o = 1-2. An Independent claim is included for the preparation of compounds (I).
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Aminomethyl substituted heterocyclic benzocycloalkene derivatives of formula (I) and their salts are new: R = OH; 1-6C alkoxy; or 3-7C cycloalkyloxy; R = 1-6C alkyl; R = 1-6C alkyl; aryl-1-2C alkyl; heterocyclyl-1-2C alkyl; -CH2-CH=C(R )2; or 3-7C cycloalkyl-methyl; R , R = H; Cl; F; CF3; 1-6C alkyl; OH; 1-6C alkoxy; 3-7C cycloalkyloxy; alpha , beta or beta , gamma -O-(CH2)o-O-; -(CH2)n-aryl; heterocyclyl; -O-(CH2)n-aryl; or alpha , beta - or beta , gamma -benzo optionally mono- or disubstituted by F, Cl, CF3, OH, 1-6C alkyl, 1-6C alkoxy or -CON(R R ); R = H or 1-6C alkyl; R = H; 1-6C alkyl; -(CH2)naryl; or CH2-3-7C cycloalkyl; or R + R = -(CH2)m or -(CH2)2-O-(CH2)2-; X = O; S; SO; or SO2; Y = -(CH2)0; -CH2-C(CH3)2-; or -C(CH3)2-; n = 0-2; m = 5-7; o = 1-2. An Independent claim is included for the preparation of compounds (I).</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BENZOCICLOALCENOS SUBSTITUIDOS E SUA UTILIZACAO COMO SUBSTANCIAS COM EFEITO ANALGESICO
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