PROCESS FOR THE PREPARATION OF IMIDAZOL DERIVATIVES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
Imidazole derivatives of the formula I wherein R1 and R2 each is lower alkyl, X is a residue of the formula R3 is hydrogen and R4 is hydrogen or lower alkyl or R3 and R4 taken together are an additional carbon-nitrogen bond; R5 is hydrogen or lower alkyl; R6 is hydrogen, lower alkyl, lower alkylthio...
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| creator | MARC MONTAVON NICOLAS SINGEWALD WILHELM KLOTZER RENATE MUSSNER |
| description | Imidazole derivatives of the formula I wherein R1 and R2 each is lower alkyl, X is a residue of the formula R3 is hydrogen and R4 is hydrogen or lower alkyl or R3 and R4 taken together are an additional carbon-nitrogen bond; R5 is hydrogen or lower alkyl; R6 is hydrogen, lower alkyl, lower alkylthio or a residue of the formula -NR7R8; and R7 and R8 each is lower alkyl or taken together with the nitrogen atom are a 5- or 6-membered saturated heterocycle; and pharmaceutically acceptable acid addition salts thereof are described. The compounds of formula I possess valuable pharmacodynamic properties, especially inflammation-inhibiting and edema-inhibiting properties, so that they can be used for the control or prevention of illnesses, especially for the control or prevention of inflammations and edemas. |
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The compounds of formula I possess valuable pharmacodynamic properties, especially inflammation-inhibiting and edema-inhibiting properties, so that they can be used for the control or prevention of illnesses, especially for the control or prevention of inflammations and edemas.</description><edition>4</edition><language>por</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1988</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19880401&DB=EPODOC&CC=PT&NR=87025A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19880401&DB=EPODOC&CC=PT&NR=87025A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MARC MONTAVON</creatorcontrib><creatorcontrib>NICOLAS SINGEWALD</creatorcontrib><creatorcontrib>WILHELM KLOTZER</creatorcontrib><creatorcontrib>RENATE MUSSNER</creatorcontrib><title>PROCESS FOR THE PREPARATION OF IMIDAZOL DERIVATIVES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME</title><description>Imidazole derivatives of the formula I wherein R1 and R2 each is lower alkyl, X is a residue of the formula R3 is hydrogen and R4 is hydrogen or lower alkyl or R3 and R4 taken together are an additional carbon-nitrogen bond; R5 is hydrogen or lower alkyl; R6 is hydrogen, lower alkyl, lower alkylthio or a residue of the formula -NR7R8; and R7 and R8 each is lower alkyl or taken together with the nitrogen atom are a 5- or 6-membered saturated heterocycle; and pharmaceutically acceptable acid addition salts thereof are described. The compounds of formula I possess valuable pharmacodynamic properties, especially inflammation-inhibiting and edema-inhibiting properties, so that they can be used for the control or prevention of illnesses, especially for the control or prevention of inflammations and edemas.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1988</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjMEKwjAQRHPxIOonCPsDgiii1yXd2IUmG5K0By-lSDyIaKH-P7bi3dPw5jEzV3cfRFOMYCRAKgl8II8BE4sDMcCWC7xIBQUFbsa6oQjoisn5EoNFTXVijRVosV4iT8s4gkvIjt35-xrR0lLNbt1jyKtfLtTaUNLlJvevNg99d83P_G59Oh23uwPu__kPCBw03g</recordid><startdate>19880401</startdate><enddate>19880401</enddate><creator>MARC MONTAVON</creator><creator>NICOLAS SINGEWALD</creator><creator>WILHELM KLOTZER</creator><creator>RENATE MUSSNER</creator><scope>EVB</scope></search><sort><creationdate>19880401</creationdate><title>PROCESS FOR THE PREPARATION OF IMIDAZOL DERIVATIVES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME</title><author>MARC MONTAVON ; NICOLAS SINGEWALD ; WILHELM KLOTZER ; RENATE MUSSNER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PT87025A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>1988</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MARC MONTAVON</creatorcontrib><creatorcontrib>NICOLAS SINGEWALD</creatorcontrib><creatorcontrib>WILHELM KLOTZER</creatorcontrib><creatorcontrib>RENATE MUSSNER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MARC MONTAVON</au><au>NICOLAS SINGEWALD</au><au>WILHELM KLOTZER</au><au>RENATE MUSSNER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR THE PREPARATION OF IMIDAZOL DERIVATIVES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME</title><date>1988-04-01</date><risdate>1988</risdate><abstract>Imidazole derivatives of the formula I wherein R1 and R2 each is lower alkyl, X is a residue of the formula R3 is hydrogen and R4 is hydrogen or lower alkyl or R3 and R4 taken together are an additional carbon-nitrogen bond; R5 is hydrogen or lower alkyl; R6 is hydrogen, lower alkyl, lower alkylthio or a residue of the formula -NR7R8; and R7 and R8 each is lower alkyl or taken together with the nitrogen atom are a 5- or 6-membered saturated heterocycle; and pharmaceutically acceptable acid addition salts thereof are described. The compounds of formula I possess valuable pharmacodynamic properties, especially inflammation-inhibiting and edema-inhibiting properties, so that they can be used for the control or prevention of illnesses, especially for the control or prevention of inflammations and edemas.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESS FOR THE PREPARATION OF IMIDAZOL DERIVATIVES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
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