PROCEDE DE PREPARATION DE DERIVES HETEROCYCLIQUES D'AMIDOXIMES ET DE COMPOSITIONS PHARMACEUTIQUES LES CONTENANT

Heterocyclic amidoxime derivatives of the general formula: wherein R' represents hydrogen or the methyl radical, and R represents the 1-oxo-1_H-isoquinolin-2-yl, 2-oxo-2_H-quinolin-1-yl, 2,3-dihydro-1_H-indol-1-yl, 1,3-dioxo-1,3-dihydro-2_H-isoindol-2-yl, 1_H-indol-1-yl, 1-oxo-1,3-dihydro-2_H-i...

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1. Verfasser:	DANIEL OBITZ
Format:	Patent
Sprache:	fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	DANIEL OBITZ
description	Heterocyclic amidoxime derivatives of the general formula: wherein R' represents hydrogen or the methyl radical, and R represents the 1-oxo-1_H-isoquinolin-2-yl, 2-oxo-2_H-quinolin-1-yl, 2,3-dihydro-1_H-indol-1-yl, 1,3-dioxo-1,3-dihydro-2_H-isoindol-2-yl, 1_H-indol-1-yl, 1-oxo-1,3-dihydro-2_H-isoindol-2-yl, 2-oxo-3,4-dihydro-2_H-quinolin-1-yl, 5-chloro-3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl, 5-chloro-2-oxo-3-phenyl-2,3-dihydro-1_H-benzimidazol-1-yl, 4-chloro-1-oxo-1_H-isoquinolin-2-yl or 3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl radical, and-when R' represents the methyl radical-racemates and enantiomers of such compounds, are new compounds useful in therapy, and especially for the treatment of complaints of the central nervous system and for the treatment of depression.
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R represents the 1-oxo-1_H-isoquinolin-2-yl, 2-oxo-2_H-quinolin-1-yl, 2,3-dihydro-1_H-indol-1-yl, 1,3-dioxo-1,3-dihydro-2_H-isoindol-2-yl, 1_H-indol-1-yl, 1-oxo-1,3-dihydro-2_H-isoindol-2-yl, 2-oxo-3,4-dihydro-2_H-quinolin-1-yl, 5-chloro-3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl, 5-chloro-2-oxo-3-phenyl-2,3-dihydro-1_H-benzimidazol-1-yl, 4-chloro-1-oxo-1_H-isoquinolin-2-yl or 3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl radical, and-when R' represents the methyl radical-racemates and enantiomers of such compounds, are new compounds useful in therapy, and especially for the treatment of complaints of the central nervous system and for the treatment of depression.</description><edition>4</edition><language>fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL 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formula: wherein R' represents hydrogen or the methyl radical, and R represents the 1-oxo-1_H-isoquinolin-2-yl, 2-oxo-2_H-quinolin-1-yl, 2,3-dihydro-1_H-indol-1-yl, 1,3-dioxo-1,3-dihydro-2_H-isoindol-2-yl, 1_H-indol-1-yl, 1-oxo-1,3-dihydro-2_H-isoindol-2-yl, 2-oxo-3,4-dihydro-2_H-quinolin-1-yl, 5-chloro-3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl, 5-chloro-2-oxo-3-phenyl-2,3-dihydro-1_H-benzimidazol-1-yl, 4-chloro-1-oxo-1_H-isoquinolin-2-yl or 3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl radical, and-when R' represents the methyl radical-racemates and enantiomers of such compounds, are new compounds useful in therapy, and especially for the treatment of complaints of the central nervous system and for the treatment of depression.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1985</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZMgPCPJ3dnVxVQCigCDXAMcgxxBPfz8FsEiQZ5hrsIKHa4grUFGks49nYCiQ76Lu6Ovp4h_h6QvkuIaAlDr7-wb4B3uCdAYrBHg4Bvk6OruGhkDU-wCxs79fiKufo18IDwNrWmJOcSovlOZmkHVzDXH20E0tyI9PLS5ITE7NSy2JDwgxN7E0NXIyJiQPABSLNnM</recordid><startdate>19850516</startdate><enddate>19850516</enddate><creator>DANIEL OBITZ</creator><scope>EVB</scope></search><sort><creationdate>19850516</creationdate><title>PROCEDE DE PREPARATION DE DERIVES HETEROCYCLIQUES D'AMIDOXIMES ET DE COMPOSITIONS PHARMACEUTIQUES LES CONTENANT</title><author>DANIEL OBITZ</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PT74952B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fre</language><creationdate>1985</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DANIEL OBITZ</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DANIEL OBITZ</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCEDE DE PREPARATION DE DERIVES HETEROCYCLIQUES D'AMIDOXIMES ET DE COMPOSITIONS PHARMACEUTIQUES LES CONTENANT</title><date>1985-05-16</date><risdate>1985</risdate><abstract>Heterocyclic amidoxime derivatives of the general formula: wherein R' represents hydrogen or the methyl radical, and R represents the 1-oxo-1_H-isoquinolin-2-yl, 2-oxo-2_H-quinolin-1-yl, 2,3-dihydro-1_H-indol-1-yl, 1,3-dioxo-1,3-dihydro-2_H-isoindol-2-yl, 1_H-indol-1-yl, 1-oxo-1,3-dihydro-2_H-isoindol-2-yl, 2-oxo-3,4-dihydro-2_H-quinolin-1-yl, 5-chloro-3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl, 5-chloro-2-oxo-3-phenyl-2,3-dihydro-1_H-benzimidazol-1-yl, 4-chloro-1-oxo-1_H-isoquinolin-2-yl or 3-methyl-2-oxo-2,3-dihydro-1_H-benzimidazol-1-yl radical, and-when R' represents the methyl radical-racemates and enantiomers of such compounds, are new compounds useful in therapy, and especially for the treatment of complaints of the central nervous system and for the treatment of depression.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	PROCEDE DE PREPARATION DE DERIVES HETEROCYCLIQUES D'AMIDOXIMES ET DE COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
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