PROCESS FOR PREPARING AQUEOUS MICELLAR SOLUTIONS OF LEVONANTRA-DOL AND N-METHYLLEVONANTRADOL

A pharmaceutical composition comprising an aqueous micellar solution of, as the active ingredient, (a) levonantradol or (b) N-methyllevonantradol, or a pharmaceutically acceptable acid addition salt of (a) or (b), and (c) at least a critical micelle concentration of a nonionic amphiphile. Also cover...

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Hauptverfasser: BIJAN RASADI, ARMANDO JOSEPH AGUIAR
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creator BIJAN RASADI
ARMANDO JOSEPH AGUIAR
description A pharmaceutical composition comprising an aqueous micellar solution of, as the active ingredient, (a) levonantradol or (b) N-methyllevonantradol, or a pharmaceutically acceptable acid addition salt of (a) or (b), and (c) at least a critical micelle concentration of a nonionic amphiphile. Also covered are pharmaceutically acceptable lyophile compositions prepared by the lyophilization of the aqueous micellar solutions. Levonantradol and N-methyllevonantradol are analgetic and anti-emetic agents.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PROCESS FOR PREPARING AQUEOUS MICELLAR SOLUTIONS OF LEVONANTRA-DOL AND N-METHYLLEVONANTRADOL
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