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A pharmaceutical composition including a mixture of active compounds (A) a pharmaceutically active polypeptide, and (B) an enhancer compound which enhances the systemic absorption of the polypeptide in the lower respiratory tract of a patient, the mixture being in the form of a dry powder for inhala...

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Bibliographische Detailangaben
Hauptverfasser: ANN CHARLOTTE BIRGIT JOHANSSON, PETER EDMAN, CARL MAGNUS OLOF DAHLBACK, KJELL GORAN ERIK BACKSTROM
Format: Patent
Sprache:por
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Beschreibung
Zusammenfassung:A pharmaceutical composition including a mixture of active compounds (A) a pharmaceutically active polypeptide, and (B) an enhancer compound which enhances the systemic absorption of the polypeptide in the lower respiratory tract of a patient, the mixture being in the form of a dry powder for inhalation in which at least 50% of the total mass of the active compounds consists of primary particles having a diameter less than or equal to about 10 microns, the primary particles optionally being formed into agglomerates.