INIBIDORES DE PROTEINA CINASE C

This invention provides novel bis-indolemaleimide macrocycle derivatives of the formula: The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.

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Bibliographische Detailangaben
Hauptverfasser:	CHRISTOPHER JOHN RITO, JOHN HAMPTON MCDONALD, III, MICHAEL ROBERT JIROUSEK, WILLIAM FRANCIS HEATH JR
Format:	Patent
Sprache:	por
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention provides novel bis-indolemaleimide macrocycle derivatives of the formula: The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.