ANTICORPOS HUMANIZADOS DIRECCIONADOS CONTRA O ANTIGENIO DE A33

A33 antigen binding proteins are described for use in the diagnosis or treatment of colorectal tumours and metastases arising therefore. The binding protein may be a humanised A33 antibody, including complete antibody molecules, fragments thereof, and, especially, multivalent monospecific proteins c...

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Bibliographische Detailangaben
Hauptverfasser:	JOHN ROBERT ADAIR, RAYMOND JOHN OWENS, DAVID JOHN KING
Format:	Patent
Sprache:	por
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A33 antigen binding proteins are described for use in the diagnosis or treatment of colorectal tumours and metastases arising therefore. The binding protein may be a humanised A33 antibody, including complete antibody molecules, fragments thereof, and, especially, multivalent monospecific proteins comprising two, three, four or more antibodies or fragments thereof bound to each other by a cross-linking agent. For diagnosis or therapy the humanised A33 antibody may be linked to a reporter or effector molecule.