POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF

The invention relates medicaments comprising novel polyethylene glycol (PEG) based prodrugs of Adrenomedullin, or one of the salts thereof, solvates thereof or the solvates of salts thereof, in combination with an inert nontoxic pharmaceutically suitable excipient, wherein the medicament is in a pha...

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Hauptverfasser: GORDEN REDLICH, FRANK WUNDER, MARIA KÖLLNBERGER, INGO FLAMME, JOHANNES KÖBBERLING, NILS GRIEBENOW, IAIN PRITCHARD, SVEN WITTROCK, RUDOLF SCHOHE-LOOP, ANDREAS KNORR, JULY MARLEY, HANS-GEORG LERCHEN
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creator GORDEN REDLICH
FRANK WUNDER
MARIA KÖLLNBERGER
INGO FLAMME
JOHANNES KÖBBERLING
NILS GRIEBENOW
IAIN PRITCHARD
SVEN WITTROCK
RUDOLF SCHOHE-LOOP
ANDREAS KNORR
JULY MARLEY
HANS-GEORG LERCHEN
description The invention relates medicaments comprising novel polyethylene glycol (PEG) based prodrugs of Adrenomedullin, or one of the salts thereof, solvates thereof or the solvates of salts thereof, in combination with an inert nontoxic pharmaceutically suitable excipient, wherein the medicament is in a pharmaceutical form for inhalation, its use for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders, to specific PEG-adrenomedullin prodrugs and its synthesis intermediates.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF
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