SOLID DISPERSION COMPRISING A HIGHLY SUBSTITUTED HYDROXYALKYL METHYLCELLULOSE

A solid dispersion comprising at least one active ingredient in at least one hydroxyalkyl methylcellulose having a DS of from 1.0 to 2.7 and an MS of from 0.40 to 1.30, wherein DS is the degree of substitution of methoxyl groups and MS is the molar substitution of hydroxyalkoxyl groups, can be produ...

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Hauptverfasser: MARK J. HALL, WESLEY J. SPAULDING, STEVEN J. GUILLAUDEU, WILLIAM W. PORTER, UMA SHRESTHA, MAUREEN L. ROSE, NICHOLAS S. GRASMAN, KEVIN P. O'DONNELL, TRUE L. ROGERS
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creator MARK J. HALL
WESLEY J. SPAULDING
STEVEN J. GUILLAUDEU
WILLIAM W. PORTER
UMA SHRESTHA
MAUREEN L. ROSE
NICHOLAS S. GRASMAN
KEVIN P. O'DONNELL
TRUE L. ROGERS
description A solid dispersion comprising at least one active ingredient in at least one hydroxyalkyl methylcellulose having a DS of from 1.0 to 2.7 and an MS of from 0.40 to 1.30, wherein DS is the degree of substitution of methoxyl groups and MS is the molar substitution of hydroxyalkoxyl groups, can be produced by extrusion or spray-drying.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title SOLID DISPERSION COMPRISING A HIGHLY SUBSTITUTED HYDROXYALKYL METHYLCELLULOSE
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