THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS
The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and...
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| creator | SÁNCHEZ-QUESADA, JORGE OLGA MARTÍNEZ MONTERO BEATRIZ RODRÍGUEZ SALGUERO JAVIER LÓPEZ OGALLA SUSANA HERRERO SANTOS MARÍA ÁNGELES PÉREZ DE LA CRUZ MORENO MIGUEL MEDINA PADILLA JAVIER DE CRISTOBAL BLANCO JUAN MANUEL DOMÍNGUEZ CORREA ANA FUERTES HUERTA FRANCISCO PALOMO NICOLAU |
| description | The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them. |
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| language | eng ; por |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS |
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