ANTI-P-SELECTIN ANTIBODIES

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suff...

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Bibliographische Detailangaben
Hauptverfasser: KAY-GUNNAR STUBENRAUCH, JACQUES HIMBER, PAUL PARREN, BEAT STEINER, ANNE STERN, ERHARD KOPETZKY, MARTINE VAN VUGT, FRANK REBERS, MIRANDA JANSEN-MOLENAAR, JAN VAN DE WINKEL, YVO GRAUS, PAMELA STREIN, DOROTHEE KLING
Format: Patent
Sprache:eng ; por
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Zusammenfassung:This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).