CONTROLLED SYNTHESIS OF ZIPRASIDONE

The subject invention provides a ziprasidone composition that comprises not greater than 1000 ppm des-chloro ziprasidone, preferably not greater than about 500 ppm des-chloro ziprasidone, and more preferably not greater than about 100 ppm des-chloro ziprasidone. Methods for synthesizing and using su...

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Hauptverfasser: HARRY RALPH JR. HOWARD, KYLE ROBERT LEEMAN, ADAM WORTH GROBIN, FRANK ROBERT BUSCH
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Sprache:eng ; por
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creator HARRY RALPH JR. HOWARD
KYLE ROBERT LEEMAN
ADAM WORTH GROBIN
FRANK ROBERT BUSCH
description The subject invention provides a ziprasidone composition that comprises not greater than 1000 ppm des-chloro ziprasidone, preferably not greater than about 500 ppm des-chloro ziprasidone, and more preferably not greater than about 100 ppm des-chloro ziprasidone. Methods for synthesizing and using such ziprasidone compositions are also provided.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CONTROLLED SYNTHESIS OF ZIPRASIDONE
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