Glycoconjugate derivative of methotrexate and glucose and method of its preparation and its use in the treatment and prevention of cancer
Przedmiotem wynalazku jest nowa glikokoniugatowa pochodna metotreksatu i glukozy oraz sposób jej otrzymywania oraz jej zastosowanie w leczeniu i zapobieganiu nowotworom, korzystnie w leczeniu i zapobieganiu nowotworom wybranym spośród: raka skóry, raka jelita grubego, raka piersi, raka żołądka, mięs...
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| creator | MAKUCH, SEBASTIAN AGRAWAL, SIDDARTH ZIÓŁKOWSKI, PIOTR SZEJA, WIESŁAW PASTUCH-GAWOŁEK, GABRIELA KRAWCZYK, MONIKA WOŹNIAK, MARTA WIŚNIEWSKI, JERZY GAMIAN, ANDRZEJ |
| description | Przedmiotem wynalazku jest nowa glikokoniugatowa pochodna metotreksatu i glukozy oraz sposób jej otrzymywania oraz jej zastosowanie w leczeniu i zapobieganiu nowotworom, korzystnie w leczeniu i zapobieganiu nowotworom wybranym spośród: raka skóry, raka jelita grubego, raka piersi, raka żołądka, mięsaka i raka płuc.
The subject of the invention is a new methotrexate-glucose conjugate derivative, its synthesis, and its use in the treatment and prevention of neoplasms, preferably in the treatment and prevention of neoplasms selected from: skin cancer, colorectal cancer, breast cancer, gastric cancer, sarcoma and lung cancer. |
| format | Patent |
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The subject of the invention is a new methotrexate-glucose conjugate derivative, its synthesis, and its use in the treatment and prevention of neoplasms, preferably in the treatment and prevention of neoplasms selected from: skin cancer, colorectal cancer, breast cancer, gastric cancer, sarcoma and lung cancer.</description><language>eng ; pol</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SUGARS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221212&DB=EPODOC&CC=PL&NR=438134A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221212&DB=EPODOC&CC=PL&NR=438134A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MAKUCH, SEBASTIAN</creatorcontrib><creatorcontrib>AGRAWAL, SIDDARTH</creatorcontrib><creatorcontrib>ZIÓŁKOWSKI, PIOTR</creatorcontrib><creatorcontrib>SZEJA, WIESŁAW</creatorcontrib><creatorcontrib>PASTUCH-GAWOŁEK, GABRIELA</creatorcontrib><creatorcontrib>KRAWCZYK, MONIKA</creatorcontrib><creatorcontrib>WOŹNIAK, MARTA</creatorcontrib><creatorcontrib>WIŚNIEWSKI, JERZY</creatorcontrib><creatorcontrib>GAMIAN, ANDRZEJ</creatorcontrib><title>Glycoconjugate derivative of methotrexate and glucose and method of its preparation and its use in the treatment and prevention of cancer</title><description>Przedmiotem wynalazku jest nowa glikokoniugatowa pochodna metotreksatu i glukozy oraz sposób jej otrzymywania oraz jej zastosowanie w leczeniu i zapobieganiu nowotworom, korzystnie w leczeniu i zapobieganiu nowotworom wybranym spośród: raka skóry, raka jelita grubego, raka piersi, raka żołądka, mięsaka i raka płuc.
The subject of the invention is a new methotrexate-glucose conjugate derivative, its synthesis, and its use in the treatment and prevention of neoplasms, preferably in the treatment and prevention of neoplasms selected from: skin cancer, colorectal cancer, breast cancer, gastric cancer, sarcoma and lung cancer.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjD0OwjAMhbswIOAM-AIMVTuwIsTPwMDAXlmpW4JaO0rcCo7ArUkKO5Of3vc9z7P3qXsZMcKPoUUlqMnbEdWOBNJAT3oX9fRMCLmGthuMhG-eYJ00qwGcJ4c-LoUnmrohmpZB7wTxCWpPrBOM8hhzcuPcIBvyy2zWYBdo9buLbH083PbnDTmpKDg0xKTV9VIW27wod3nx3_gAUyBMLw</recordid><startdate>20221212</startdate><enddate>20221212</enddate><creator>MAKUCH, SEBASTIAN</creator><creator>AGRAWAL, SIDDARTH</creator><creator>ZIÓŁKOWSKI, PIOTR</creator><creator>SZEJA, WIESŁAW</creator><creator>PASTUCH-GAWOŁEK, GABRIELA</creator><creator>KRAWCZYK, MONIKA</creator><creator>WOŹNIAK, MARTA</creator><creator>WIŚNIEWSKI, JERZY</creator><creator>GAMIAN, ANDRZEJ</creator><scope>EVB</scope></search><sort><creationdate>20221212</creationdate><title>Glycoconjugate derivative of methotrexate and glucose and method of its preparation and its use in the treatment and prevention of cancer</title><author>MAKUCH, SEBASTIAN ; AGRAWAL, SIDDARTH ; ZIÓŁKOWSKI, PIOTR ; SZEJA, WIESŁAW ; PASTUCH-GAWOŁEK, GABRIELA ; KRAWCZYK, MONIKA ; WOŹNIAK, MARTA ; WIŚNIEWSKI, JERZY ; GAMIAN, ANDRZEJ</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PL438134A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; pol</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>MAKUCH, SEBASTIAN</creatorcontrib><creatorcontrib>AGRAWAL, SIDDARTH</creatorcontrib><creatorcontrib>ZIÓŁKOWSKI, PIOTR</creatorcontrib><creatorcontrib>SZEJA, WIESŁAW</creatorcontrib><creatorcontrib>PASTUCH-GAWOŁEK, GABRIELA</creatorcontrib><creatorcontrib>KRAWCZYK, MONIKA</creatorcontrib><creatorcontrib>WOŹNIAK, MARTA</creatorcontrib><creatorcontrib>WIŚNIEWSKI, JERZY</creatorcontrib><creatorcontrib>GAMIAN, ANDRZEJ</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MAKUCH, SEBASTIAN</au><au>AGRAWAL, SIDDARTH</au><au>ZIÓŁKOWSKI, PIOTR</au><au>SZEJA, WIESŁAW</au><au>PASTUCH-GAWOŁEK, GABRIELA</au><au>KRAWCZYK, MONIKA</au><au>WOŹNIAK, MARTA</au><au>WIŚNIEWSKI, JERZY</au><au>GAMIAN, ANDRZEJ</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Glycoconjugate derivative of methotrexate and glucose and method of its preparation and its use in the treatment and prevention of cancer</title><date>2022-12-12</date><risdate>2022</risdate><abstract>Przedmiotem wynalazku jest nowa glikokoniugatowa pochodna metotreksatu i glukozy oraz sposób jej otrzymywania oraz jej zastosowanie w leczeniu i zapobieganiu nowotworom, korzystnie w leczeniu i zapobieganiu nowotworom wybranym spośród: raka skóry, raka jelita grubego, raka piersi, raka żołądka, mięsaka i raka płuc.
The subject of the invention is a new methotrexate-glucose conjugate derivative, its synthesis, and its use in the treatment and prevention of neoplasms, preferably in the treatment and prevention of neoplasms selected from: skin cancer, colorectal cancer, breast cancer, gastric cancer, sarcoma and lung cancer.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | Glycoconjugate derivative of methotrexate and glucose and method of its preparation and its use in the treatment and prevention of cancer |
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