C-14 OXIDATION OF MORPHINE DERIVATIVES

The present invention relates to process for the preparation of a 14-hydroxynormorphinone derivative of formula IV comprising reacting the compound of formula III, with a cobalt (II) oxidant in the presence of a mild base and air or oxygen as the cooxidant; wherein R1 is (1C-7C)alkyl optionally subs...

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Bibliographische Detailangaben

Hauptverfasser:	LINDERS JOANNES THEODORUS MARIA, VRIJHOF PIETER
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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