COMPOSITIONS RELATING TO A MUTANT CLOSTRIDIUM DIFFICILE TOXIN AND METHODS THEREOF

In one aspect, the invention relates to an immunogenic composition that includes a mutant Clostridium difficile toxin A and/or a mutant Clostridium difficile toxin B. Each mutant toxin includes a glucosyltransferase domain having at least one mutation and a cysteine protease domain having at least o...

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Hauptverfasser: KALYAN, NARENDER K, JANSEN, KATHRIN UTE, MORAN, JUSTIN KEITH, FLINT, MICHAEL JAMES, SIDHU, MANINDER K, MININNI, TERRI L, ANDERSON, ANNALIESA SYBIL, DONALD, ROBERT G. K, RUPPEN, MARK E
Format: Patent
Sprache:eng ; pol
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