NOVEL CEPHALOTAXANE DERIVATIVES AND PROCESS FOR THEIR PREPARATION

The present invention concerns a new general process for asymmetric hemisynthesis of harringtonines and their analogs, that are alkaloids used in chemotherapy. This process comprises direct esterification of a natural cephalotaxine with an acylating compound constituted of a side chain precursor whi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	ROUAUD SYLVIE, MEVELEC LAURENCE, GILET CHRYSTELLE, CAVOLEAU SYLVIE, POUTOT SANDRINE, CHARBONNEL SANDRA, ROBIN JEAN-PIERRE, DHAL ROBERT, FOURNIER FLORENCE, DUJARDIN GILLES, ROBIN JULIE, CHAUVIAT LUDOVIC, GIRODIER LAURENT
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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