METHOD OF SYNTHESISING INHIBITORS OF HIV PROTEASE
An improved process for the synthesis of (3S)-tetrahydro-3-furyl N-[(1S,2R)-3 -(4-amino-N-isobutylbenzenesulphonamido)-1-benzyl-2-hydroxypropyl]carbamate comprising four steps form the compound of formula A and a novel intermediate thereto.
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| creator | O'CALLAGHAN JOHN AL-FARHAN EMILE RODGERS KEITH ROUT STEPHEN JOHN SINGH HARDEV TUNG ROGER DENNIS DEININGER DAVID D MCGHIE STEPHEN ROBERTSON MARK STUART |
| description | An improved process for the synthesis of (3S)-tetrahydro-3-furyl N-[(1S,2R)-3 -(4-amino-N-isobutylbenzenesulphonamido)-1-benzyl-2-hydroxypropyl]carbamate comprising four steps form the compound of formula A and a novel intermediate thereto. |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | METHOD OF SYNTHESISING INHIBITORS OF HIV PROTEASE |
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