GEL COMPOSITIONS
The present invention provides a gel combination comprising: polycarbophil in an amount comprised from 1 to 5% by weight; polyvinylpirrolidone in an amount comprised from 4 to 8% by weight; glycerine in an amount comprised from 1 to 10% by weight; and propyleneglycol in an amount comprised from 20 t...
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creator | DA COSTA MARTINS RAQUEL MARIA PÉREZ LOZANO PILAR GARCÍA MONTOYA ENCARNA MIÑARRO CARMONA MONTSERRAT SÁNCHEZ PORQUERES NATALIA SUÑÉ NEGRE JOSEP M GONZÁLEZ OJER CARLOS TICÓ GRAU JOSEP RAMON ROIG CARRERAS MANEL |
description | The present invention provides a gel combination comprising: polycarbophil in an amount comprised from 1 to 5% by weight; polyvinylpirrolidone in an amount comprised from 4 to 8% by weight; glycerine in an amount comprised from 1 to 10% by weight; and propyleneglycol in an amount comprised from 20 to 40% by weight; wherein: the weight ratio between polyvinylpirrolidone:polycarbophil is comprised between 1:1 and 4:1, the weight ratio between glycerine:polycarbophil is comprised from 0.5:1 to 2:1, and the weight ratio propyleneglycol:polycarbophil is comprised from 8:1 to 20:1. The invention also provides transparent compositions comprising such gel combinations as well as processes for their preparation and the use thereof as a medicament. Due to the specific excipients, % by weight, and weight ratios forming the combination, the resulting compositions show a high bioadhesivity and bioavailablity of the active ingredient, without toxic adverse effects. |
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The invention also provides transparent compositions comprising such gel combinations as well as processes for their preparation and the use thereof as a medicament. 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The invention also provides transparent compositions comprising such gel combinations as well as processes for their preparation and the use thereof as a medicament. 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The invention also provides transparent compositions comprising such gel combinations as well as processes for their preparation and the use thereof as a medicament. Due to the specific excipients, % by weight, and weight ratios forming the combination, the resulting compositions show a high bioadhesivity and bioavailablity of the active ingredient, without toxic adverse effects.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | GEL COMPOSITIONS |
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