Agents targeting CD138 and uses thereof

Disclosed is a human murine chimeric antibody which substantially retains the antigen binding region of its murine counterpart and displays improved binding affinities to the antigen and/or ore homogenous binding to target cells.

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Bibliographische Detailangaben
Hauptverfasser:	DAELKEN, BENJAMIN, GERMER, MATTHIAS, ZENG, STEFFEN, UHEREK, CHRISTOPH, AIGNER, SILKE, KRAUS, ELMAR, BRUECHER, CHRISTOPH, SCHULZ, GREGOR, OSTERROTH, FRANK
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed is a human murine chimeric antibody which substantially retains the antigen binding region of its murine counterpart and displays improved binding affinities to the antigen and/or ore homogenous binding to target cells.