DOSAGE FORMS OF APIXABAN

DOSAGE FORMS OF APIXABAN

The present invention provides a process for producing a solid amorphous dispersion of apixaban comprising dissolving apixaban and one or more polymers in a solvent, which dissolves both apixaban and the one or more polymers and removing the solvent by spray drying; a solid amorphous dispersion prep...

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1. Verfasser: NAUSE, RICHARD G
Format: Patent
Sprache:eng ; pol
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator NAUSE, RICHARD G
description The present invention provides a process for producing a solid amorphous dispersion of apixaban comprising dissolving apixaban and one or more polymers in a solvent, which dissolves both apixaban and the one or more polymers and removing the solvent by spray drying; a solid amorphous dispersion prepared according to the process; as well as a dosage form comprising the solid amorphous dispersion.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DOSAGE FORMS OF APIXABAN
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