TETRASUBSTITUTED PYRIDAZINE AS HEDGEHOG PATHWAY ANTAGONISTS

The present invention provides novel tetrasubstituted pyridine hedgehog pathway antagonists of the following formula I (I) or a pharmaceutically acceptable salt thereof, wherein: X is C-R1 or N; R1 is hydrogen, fluoro or cyano; R2 is formula II (II), piperidinyl, or gem di-F-substituted cyclohexyl;...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	HIPSKIND, PHILIP ARTHUR, THOMPSON, MICHELLE LEE, WILSON (NEE TAKAKUWA), TAKAKO, COHEN, JEFFREY DANIEL, CLAY, JULIA MARIE, SALL, DANIEL JON, BASTIAN, JOLIE ANNE, LOBB, KAREN LYNN
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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