TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS

Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases.

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Hauptverfasser: LYSSIKATOS, JOSEPH P, MUNSON, MARK C, RAST, BRYSON, DELISLE, ROBERT KIRK, GROSS, STEFAN D, DAVIS, T. GREGG, TOPALOV, GEORGE T, HICKEN, ERIK JAMES, WRIGHT, A. DALE, CELESTE, LAURA L, ROBINSON, JOHN E, ZHAO, QIAN, KALLAN, NICHOLAS C, PHENEGER, JED, GRESCHUK, JULIE MARIE, ALLEN, SHELLEY, MARMSATER, FREDRIK P, JACKSON, LEILA J, SCHLACHTER, STEPHEN T
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creator LYSSIKATOS, JOSEPH P
MUNSON, MARK C
RAST, BRYSON
DELISLE, ROBERT KIRK
GROSS, STEFAN D
DAVIS, T. GREGG
TOPALOV, GEORGE T
HICKEN, ERIK JAMES
WRIGHT, A. DALE
CELESTE, LAURA L
ROBINSON, JOHN E
ZHAO, QIAN
KALLAN, NICHOLAS C
PHENEGER, JED
GRESCHUK, JULIE MARIE
ALLEN, SHELLEY
MARMSATER, FREDRIK P
JACKSON, LEILA J
SCHLACHTER, STEPHEN T
description Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS
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