PIPERAZINE SALTS AS D3/D2 ANTAGONISTS

The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans 4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cyclohexylamine and/or their hydrates and/or solvates. Moreover, the invention relates...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SEBÖK, FERENC, ÁGAINÉ CSONGOR, ÉVA, DOMÁNY, GYÖRGY, CZIBULA, LÁSZLÓ, GREINER, ISTVÁN
Format: Patent
Sprache:eng ; pol
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator SEBÖK, FERENC
ÁGAINÉ CSONGOR, ÉVA
DOMÁNY, GYÖRGY
CZIBULA, LÁSZLÓ
GREINER, ISTVÁN
description The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans 4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cyclohexylamine and/or their hydrates and/or solvates. Moreover, the invention relates to the process for preparing the salts and their hydrates and/or solvates, to their use in the treatment and/or prevention of conditions which require modulation of dopamine receptor and to pharmaceutical compositions containing them.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_PL2155696TT3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>PL2155696TT3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_PL2155696TT33</originalsourceid><addsrcrecordid>eNrjZFAN8AxwDXKM8vRzVQh29AkJVnAMVnAx1ncxUnD0C3F09_fzDA4J5mFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8QE-RoampmaWZiEhxsbEqAEAkzsjkw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PIPERAZINE SALTS AS D3/D2 ANTAGONISTS</title><source>esp@cenet</source><creator>SEBÖK, FERENC ; ÁGAINÉ CSONGOR, ÉVA ; DOMÁNY, GYÖRGY ; CZIBULA, LÁSZLÓ ; GREINER, ISTVÁN</creator><creatorcontrib>SEBÖK, FERENC ; ÁGAINÉ CSONGOR, ÉVA ; DOMÁNY, GYÖRGY ; CZIBULA, LÁSZLÓ ; GREINER, ISTVÁN</creatorcontrib><description>The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans 4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cyclohexylamine and/or their hydrates and/or solvates. Moreover, the invention relates to the process for preparing the salts and their hydrates and/or solvates, to their use in the treatment and/or prevention of conditions which require modulation of dopamine receptor and to pharmaceutical compositions containing them.</description><language>eng ; pol</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20171031&amp;DB=EPODOC&amp;CC=PL&amp;NR=2155696T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20171031&amp;DB=EPODOC&amp;CC=PL&amp;NR=2155696T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SEBÖK, FERENC</creatorcontrib><creatorcontrib>ÁGAINÉ CSONGOR, ÉVA</creatorcontrib><creatorcontrib>DOMÁNY, GYÖRGY</creatorcontrib><creatorcontrib>CZIBULA, LÁSZLÓ</creatorcontrib><creatorcontrib>GREINER, ISTVÁN</creatorcontrib><title>PIPERAZINE SALTS AS D3/D2 ANTAGONISTS</title><description>The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans 4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cyclohexylamine and/or their hydrates and/or solvates. Moreover, the invention relates to the process for preparing the salts and their hydrates and/or solvates, to their use in the treatment and/or prevention of conditions which require modulation of dopamine receptor and to pharmaceutical compositions containing them.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAN8AxwDXKM8vRzVQh29AkJVnAMVnAx1ncxUnD0C3F09_fzDA4J5mFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8QE-RoampmaWZiEhxsbEqAEAkzsjkw</recordid><startdate>20171031</startdate><enddate>20171031</enddate><creator>SEBÖK, FERENC</creator><creator>ÁGAINÉ CSONGOR, ÉVA</creator><creator>DOMÁNY, GYÖRGY</creator><creator>CZIBULA, LÁSZLÓ</creator><creator>GREINER, ISTVÁN</creator><scope>EVB</scope></search><sort><creationdate>20171031</creationdate><title>PIPERAZINE SALTS AS D3/D2 ANTAGONISTS</title><author>SEBÖK, FERENC ; ÁGAINÉ CSONGOR, ÉVA ; DOMÁNY, GYÖRGY ; CZIBULA, LÁSZLÓ ; GREINER, ISTVÁN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PL2155696TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; pol</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SEBÖK, FERENC</creatorcontrib><creatorcontrib>ÁGAINÉ CSONGOR, ÉVA</creatorcontrib><creatorcontrib>DOMÁNY, GYÖRGY</creatorcontrib><creatorcontrib>CZIBULA, LÁSZLÓ</creatorcontrib><creatorcontrib>GREINER, ISTVÁN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SEBÖK, FERENC</au><au>ÁGAINÉ CSONGOR, ÉVA</au><au>DOMÁNY, GYÖRGY</au><au>CZIBULA, LÁSZLÓ</au><au>GREINER, ISTVÁN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PIPERAZINE SALTS AS D3/D2 ANTAGONISTS</title><date>2017-10-31</date><risdate>2017</risdate><abstract>The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans 4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cyclohexylamine and/or their hydrates and/or solvates. Moreover, the invention relates to the process for preparing the salts and their hydrates and/or solvates, to their use in the treatment and/or prevention of conditions which require modulation of dopamine receptor and to pharmaceutical compositions containing them.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; pol
recordid cdi_epo_espacenet_PL2155696TT3
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PIPERAZINE SALTS AS D3/D2 ANTAGONISTS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T18%3A17%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SEB%C3%96K,%20FERENC&rft.date=2017-10-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EPL2155696TT3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true