3, 4-di-substituted cyclobuten-1, 2-diones as CXC chemokine receptor ligands
There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
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| creator | LI GE FERREIRA JOHAN A CHAO JIANHUA TAVERAS ARTHUR G KAISER BERND YU YOUNONG CHAO JIANPING MERRITT J. ROBERT NELSON KINGSLEY H DWYER MICHAEL ROKOSZ LAURA L BOND RICHARD W AKI CYNTHIA J BALDWIN JOHN J |
| description | There are disclosed compounds of the formula
or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer. |
| format | Patent |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 3, 4-di-substituted cyclobuten-1, 2-diones as CXC chemokine receptor ligands |
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