IMPROVED METHOD OF PRODUCTION OF 9-CIS-RETINOIC ACID

Improved method of production of 9-(Z)-retinoic acid, in which a) a beta-formyl-crotonic acid C1-C10 alkyl or phenyl ester is reacted with an isolated 9-(Z)-C15-triarylphosphonium salt by the Wittig reaction in the presence of a base to the corresponding 9-(Z)-retinoic acid ester; which b) is then s...

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Bibliographische Detailangaben
Hauptverfasser: STANEK, MICHAEL, KNOPP, MONIKA, KÜBEL, ERWIN, ESSL, STEFAN
Format: Patent
Sprache:eng ; pol
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