2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS

Provided are compounds of formula I that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes mellitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase...

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Hauptverfasser: HINKLIN, RONALD JAY, SINGH, AJAY, CONDROSKI, KEVIN RONALD, AICHER, THOMAS DANIEL, CHICARELLI, MARK JOSEPH, BOYD, STEVEN ARMEN
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creator HINKLIN, RONALD JAY
SINGH, AJAY
CONDROSKI, KEVIN RONALD
AICHER, THOMAS DANIEL
CHICARELLI, MARK JOSEPH
BOYD, STEVEN ARMEN
description Provided are compounds of formula I that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes mellitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase or which can be treated by activating glucokinase.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS
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