Method for manufacture of (5Z,25S)-25-cyclohexyl- 4'-O-de-(2,6-dideoxy-3-O-methyl-alpha-L -arabinohexopyranosyl)-5-demethoxy-25-de-(1-methylpropyl)-22,23-dihydro-5-hydro-Al xyiminoavermectine, (25S)-25-cyclohexyl-4'-O-de-(2,6-dideoxy-3-)-methyl-alpha-L-ar

Method for manufacture of (5Z,25S)-25-cyclohexyl- 4'-O-de-(2,6-dideoxy-3-O-methyl-alpha-L -arabinohexopyranosyl)-5-demethoxy-25-de-(1-methylpropyl)-22,23-dihydro-5-hydro-Al xyiminoavermectine, (25S)-25-cyclohexyl-4'-O-de-(2,6-dideoxy-3-)-methyl-alpha-L-ar

An improved process for the preparation of the antiparasitic compound 25-cyclohexyl-22,23-dihydro-5-hydroxyiminoavermectin B1 monosaccharide from doramectine and intermediates therefor and crystalline solvates thereof.

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Bibliographische Detailangaben
Hauptverfasser: CAMBERS SELENA JANE, WALSHE NIGEL DEREK ARTHUR
Format: Patent
Sprache:eng ; pol
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Beschreibung
Zusammenfassung:An improved process for the preparation of the antiparasitic compound 25-cyclohexyl-22,23-dihydro-5-hydroxyiminoavermectin B1 monosaccharide from doramectine and intermediates therefor and crystalline solvates thereof.