NOVEL SUBSTITUTED THIOPHENEPYRIMIDINONE DERIVATIVES AS INHIBITORS OF 17ß-HYDROXYSTEROID DEHYDROGENASE

This invention relates to novel substituted thiophenepyrimidinone derivatives and their use in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent diseases or disorder, such as steroid hormone dependent diseases or disorders requiring inhibition of 17ß-hydro...

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Hauptverfasser: KOSKIMIES, PASI, THOLE, HEINRICH-HUBERT, KIVINIEMI, JOHANNA, LEHTOVUORI, PEKKA, MESSINGER, JOSEF, KALLIO, LILA, HIRVELÄ, LEENA, HUSEN, BETTINA, UNKILA, MIKKO, SAARENKETO, PAULI, VAN STEEN, BARTHOLOMEUS JOHANNES, PENTIKÄINEN, OLLI TANELI
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creator KOSKIMIES, PASI
THOLE, HEINRICH-HUBERT
KIVINIEMI, JOHANNA
LEHTOVUORI, PEKKA
MESSINGER, JOSEF
KALLIO, LILA
HIRVELÄ, LEENA
HUSEN, BETTINA
UNKILA, MIKKO
SAARENKETO, PAULI
VAN STEEN, BARTHOLOMEUS JOHANNES
PENTIKÄINEN, OLLI TANELI
description This invention relates to novel substituted thiophenepyrimidinone derivatives and their use in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent diseases or disorder, such as steroid hormone dependent diseases or disorders requiring inhibition of 17ß-hydroxysteroid dehydrogenase enzymes.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title NOVEL SUBSTITUTED THIOPHENEPYRIMIDINONE DERIVATIVES AS INHIBITORS OF 17ß-HYDROXYSTEROID DEHYDROGENASE
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