DELIVERY OF PARTICLES

A needleless syringe capable of accelerating particles comprising a therapeutic agent across skin or mucosal tissue of a vertebrate subject is provided. The syringe comprises a body having a lumen with a diaphragm located adjacent to a terminus thereof. Particles comprising a therapeutic agent are d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BELLHOUSE BRIAN J, BELL JOHN
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:A needleless syringe capable of accelerating particles comprising a therapeutic agent across skin or mucosal tissue of a vertebrate subject is provided. The syringe comprises a body having a lumen with a diaphragm located adjacent to a terminus thereof. Particles comprising a therapeutic agent are delivered from an external surface of the diaphragm by means of the motive force provided by the impact of a gaseous shock upon the internal surface of the diaphragm. A method for transdermally delivering particles comprising a therapeutic agent from the needleless syringe is also provided.