ENANTIOMERICALLY PURE AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS

Enantiomerically pure compound of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.

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Hauptverfasser: FUNK, LEE A, JIA, LEI, PAIRISH, MASON A, KUNG, PEI-PEI, TRAN-DUBE, M. B, CUI, JINGRONG J, NAMBU, MITCHELL D, MENG, JERRY J, SHEN, HONG
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creator FUNK, LEE A
JIA, LEI
PAIRISH, MASON A
KUNG, PEI-PEI
TRAN-DUBE, M. B
CUI, JINGRONG J
NAMBU, MITCHELL D
MENG, JERRY J
SHEN, HONG
description Enantiomerically pure compound of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title ENANTIOMERICALLY PURE AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS
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