METHOD OF OBTAINING NOVEL OXAZOLYL DERIVATIVES
Oxazolyl derivatives of formula (I), wherein -A =A -A =A - represents a bivalent radical having the formula -CH=CH-CH=CH- (a-1), -N=CH-CH=CH- (a-2), -CH=N-CH=CH- (a-3), -CH=CH-N=CH- (a-4), -CH=CH-CH=N- (a-5), -N=CH-N=CH- (a-6) or -CH=N-CH=N- (a-7); R represents hydrogen or C1-4alkyl; R represents hy...
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| creator | DIERCKX ANN CH. J SOMMEN FRANCOIS M COOYMANS LUDWIG P JANSSENS FRANS E |
| description | Oxazolyl derivatives of formula (I), wherein -A =A -A =A - represents a bivalent radical having the formula -CH=CH-CH=CH- (a-1), -N=CH-CH=CH- (a-2), -CH=N-CH=CH- (a-3), -CH=CH-N=CH- (a-4), -CH=CH-CH=N- (a-5), -N=CH-N=CH- (a-6) or -CH=N-CH=N- (a-7); R represents hydrogen or C1-4alkyl; R represents hydrogen, C1-6alkyl or hydroxy-C1-6alkyl; m represents 1 or 2; D represents C1-4alkanediyl; B represents NR , CH2, O, S, SO or SO2 wherein R is hydrogen or C1-4alkyl; n represents 0, 1 or 2; L represents hydrogen; C1-12alkyl; C3-6cycloalkyl; C3-6alkenyl optionally substituted with aryl; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl; arylcarbonyl; arylC1-6 alkyloxycarbonyl; or a radical of formula -Alk-R (b-1); -Alk-Y-R (b-2); -Alk-Z -C(=X)-Z -R (b-3); or -CH2-CHOH-CH2-O-R (b-4), the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof have antiallergic properties. Compositions containing the same and methods of treating warm-blooded animals suffering from allergic diseases. |
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J ; SOMMEN FRANCOIS M ; COOYMANS LUDWIG P ; JANSSENS FRANS E</creatorcontrib><description>Oxazolyl derivatives of formula (I), wherein -A =A -A =A - represents a bivalent radical having the formula -CH=CH-CH=CH- (a-1), -N=CH-CH=CH- (a-2), -CH=N-CH=CH- (a-3), -CH=CH-N=CH- (a-4), -CH=CH-CH=N- (a-5), -N=CH-N=CH- (a-6) or -CH=N-CH=N- (a-7); R represents hydrogen or C1-4alkyl; R represents hydrogen, C1-6alkyl or hydroxy-C1-6alkyl; m represents 1 or 2; D represents C1-4alkanediyl; B represents NR , CH2, O, S, SO or SO2 wherein R is hydrogen or C1-4alkyl; n represents 0, 1 or 2; L represents hydrogen; C1-12alkyl; C3-6cycloalkyl; C3-6alkenyl optionally substituted with aryl; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl; arylcarbonyl; arylC1-6 alkyloxycarbonyl; or a radical of formula -Alk-R (b-1); -Alk-Y-R (b-2); -Alk-Z -C(=X)-Z -R (b-3); or -CH2-CHOH-CH2-O-R (b-4), the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof have antiallergic properties. Compositions containing the same and methods of treating warm-blooded animals suffering from allergic diseases.</description><edition>6</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960731&DB=EPODOC&CC=PL&NR=169361B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960731&DB=EPODOC&CC=PL&NR=169361B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DIERCKX ANN CH. J</creatorcontrib><creatorcontrib>SOMMEN FRANCOIS M</creatorcontrib><creatorcontrib>COOYMANS LUDWIG P</creatorcontrib><creatorcontrib>JANSSENS FRANS E</creatorcontrib><title>METHOD OF OBTAINING NOVEL OXAZOLYL DERIVATIVES</title><description>Oxazolyl derivatives of formula (I), wherein -A =A -A =A - represents a bivalent radical having the formula -CH=CH-CH=CH- (a-1), -N=CH-CH=CH- (a-2), -CH=N-CH=CH- (a-3), -CH=CH-N=CH- (a-4), -CH=CH-CH=N- (a-5), -N=CH-N=CH- (a-6) or -CH=N-CH=N- (a-7); R represents hydrogen or C1-4alkyl; R represents hydrogen, C1-6alkyl or hydroxy-C1-6alkyl; m represents 1 or 2; D represents C1-4alkanediyl; B represents NR , CH2, O, S, SO or SO2 wherein R is hydrogen or C1-4alkyl; n represents 0, 1 or 2; L represents hydrogen; C1-12alkyl; C3-6cycloalkyl; C3-6alkenyl optionally substituted with aryl; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl; arylcarbonyl; arylC1-6 alkyloxycarbonyl; or a radical of formula -Alk-R (b-1); -Alk-Y-R (b-2); -Alk-Z -C(=X)-Z -R (b-3); or -CH2-CHOH-CH2-O-R (b-4), the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof have antiallergic properties. Compositions containing the same and methods of treating warm-blooded animals suffering from allergic diseases.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1996</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDzdQ3x8HdR8HdT8HcKcfT08_RzV_DzD3P1UfCPcIzy94n0UXBxDfIMcwzxDHMN5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8QE-hmaWxmaGTk6GxkQoAQCyVyXC</recordid><startdate>19960731</startdate><enddate>19960731</enddate><creator>DIERCKX ANN CH. J</creator><creator>SOMMEN FRANCOIS M</creator><creator>COOYMANS LUDWIG P</creator><creator>JANSSENS FRANS E</creator><scope>EVB</scope></search><sort><creationdate>19960731</creationdate><title>METHOD OF OBTAINING NOVEL OXAZOLYL DERIVATIVES</title><author>DIERCKX ANN CH. J ; SOMMEN FRANCOIS M ; COOYMANS LUDWIG P ; JANSSENS FRANS E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PL169361BB13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1996</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DIERCKX ANN CH. J</creatorcontrib><creatorcontrib>SOMMEN FRANCOIS M</creatorcontrib><creatorcontrib>COOYMANS LUDWIG P</creatorcontrib><creatorcontrib>JANSSENS FRANS E</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DIERCKX ANN CH. J</au><au>SOMMEN FRANCOIS M</au><au>COOYMANS LUDWIG P</au><au>JANSSENS FRANS E</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF OBTAINING NOVEL OXAZOLYL DERIVATIVES</title><date>1996-07-31</date><risdate>1996</risdate><abstract>Oxazolyl derivatives of formula (I), wherein -A =A -A =A - represents a bivalent radical having the formula -CH=CH-CH=CH- (a-1), -N=CH-CH=CH- (a-2), -CH=N-CH=CH- (a-3), -CH=CH-N=CH- (a-4), -CH=CH-CH=N- (a-5), -N=CH-N=CH- (a-6) or -CH=N-CH=N- (a-7); R represents hydrogen or C1-4alkyl; R represents hydrogen, C1-6alkyl or hydroxy-C1-6alkyl; m represents 1 or 2; D represents C1-4alkanediyl; B represents NR , CH2, O, S, SO or SO2 wherein R is hydrogen or C1-4alkyl; n represents 0, 1 or 2; L represents hydrogen; C1-12alkyl; C3-6cycloalkyl; C3-6alkenyl optionally substituted with aryl; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl; arylcarbonyl; arylC1-6 alkyloxycarbonyl; or a radical of formula -Alk-R (b-1); -Alk-Y-R (b-2); -Alk-Z -C(=X)-Z -R (b-3); or -CH2-CHOH-CH2-O-R (b-4), the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof have antiallergic properties. Compositions containing the same and methods of treating warm-blooded animals suffering from allergic diseases.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | METHOD OF OBTAINING NOVEL OXAZOLYL DERIVATIVES |
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