A METHOD FOR THE PREPARATION OF ENANTIOMERICALLY PURE MIRTAZAPINE

The invention provides a method for the preparation of enantiomerically pure mirtazapine, said method comprising a step of ring closure of a compound of formula (II) wherein X is a leaving group, said step comprising treatment with an acid, whereby mirlazapine with enantiomeric excess is formed by t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VAN DE VEN, ADRIANUS ANTONIUS MARTINUS, KEMPERMAN, GERARDUS JOHANNES, WIERINGA, JOHANNES HUBERTUS
Format: Patent
Sprache:eng ; pol
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