PREPARATION METHOD FOR NEW PIPERIDINE DERIVATIVES

The (3R,S)- or (3R)- form of a compound of the formula:- or a pharmaceutically acceptable salt thereof, wherein R is a group of the formula:- where each Y, which may be the same or different, is selected from the substituents hydrogen, halo and C1-C4 alkyl: X is -(CH2)2-, -CH=CH-, -CH2-S-, -CH2-O-,...

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Hauptverfasser: ALKER DAVID, CROSS PETER E, WALLIS ROBERT M
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creator ALKER DAVID
CROSS PETER E
WALLIS ROBERT M
description The (3R,S)- or (3R)- form of a compound of the formula:- or a pharmaceutically acceptable salt thereof, wherein R is a group of the formula:- where each Y, which may be the same or different, is selected from the substituents hydrogen, halo and C1-C4 alkyl: X is -(CH2)2-, -CH=CH-, -CH2-S-, -CH2-O-, -S- or -O-; and R is a group of the formula:- wherein R , R , R and R are certain specified substituents. The compounds are useful in the treatment of diseases associated with altered motility and/or tone of smooth muscle.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PREPARATION METHOD FOR NEW PIPERIDINE DERIVATIVES
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