5-OXO-6-HYDROXY-4,5-DIHYDRO-1,2,5-TRIAZIN-3YL-THIOMETHYL SUBSTITUTED DERIVATIVES OF CEPHALOSPORIN
Novel cephalosporins of the general formula are obtained by reaction of a 3-acetoxymethylcephalosporin of the formula with a triazinylthio derivative of the formula The substituents are defined in Claim 1. If necessary, the amino and/or carboxyl groups are intermediately protected and, if it is desi...
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| creator | LUNN WILLIAM HENRY WALKER |
| description | Novel cephalosporins of the general formula are obtained by reaction of a 3-acetoxymethylcephalosporin of the formula with a triazinylthio derivative of the formula The substituents are defined in Claim 1. If necessary, the amino and/or carboxyl groups are intermediately protected and, if it is desired, the compounds obtained according to the invention are acylated by the known processes. The reaction is preferably carried out in polar solvents, e.g. water. These novel cephalosporins are to be used on the one hand as medicines having antibiotic activity or on the other hand as intermediates in the preparation of antibiotics. |
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If necessary, the amino and/or carboxyl groups are intermediately protected and, if it is desired, the compounds obtained according to the invention are acylated by the known processes. The reaction is preferably carried out in polar solvents, e.g. water. These novel cephalosporins are to be used on the one hand as medicines having antibiotic activity or on the other hand as intermediates in the preparation of antibiotics.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1983</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19830620&DB=EPODOC&CC=PH&NR=16078A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19830620&DB=EPODOC&CC=PH&NR=16078A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LUNN WILLIAM HENRY WALKER</creatorcontrib><title>5-OXO-6-HYDROXY-4,5-DIHYDRO-1,2,5-TRIAZIN-3YL-THIOMETHYL SUBSTITUTED DERIVATIVES OF CEPHALOSPORIN</title><description>Novel cephalosporins of the general formula are obtained by reaction of a 3-acetoxymethylcephalosporin of the formula with a triazinylthio derivative of the formula The substituents are defined in Claim 1. If necessary, the amino and/or carboxyl groups are intermediately protected and, if it is desired, the compounds obtained according to the invention are acylated by the known processes. The reaction is preferably carried out in polar solvents, e.g. water. These novel cephalosporins are to be used on the one hand as medicines having antibiotic activity or on the other hand as intermediates in the preparation of antibiotics.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1983</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFycEKgkAQgGEvHaJ6hGAfwIHMtK6bu7ID1sjuKG4XkdhOUYK9P0V07_Tz8c-jIQPqCHIwXlnqPOziDBR-BUm8_YgtygueIfUVsEE6aTa-Eq45OkZuWCuhtMVWMrbaCSpFoWsjK3I1WTwvo9ltuE9h9esiWpeaCwNhfPZhGodreIRXX5sk3-wPMv333_7bMhE</recordid><startdate>19830620</startdate><enddate>19830620</enddate><creator>LUNN WILLIAM HENRY WALKER</creator><scope>EVB</scope></search><sort><creationdate>19830620</creationdate><title>5-OXO-6-HYDROXY-4,5-DIHYDRO-1,2,5-TRIAZIN-3YL-THIOMETHYL SUBSTITUTED DERIVATIVES OF CEPHALOSPORIN</title><author>LUNN WILLIAM HENRY WALKER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PH16078A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1983</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LUNN WILLIAM HENRY WALKER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LUNN WILLIAM HENRY WALKER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>5-OXO-6-HYDROXY-4,5-DIHYDRO-1,2,5-TRIAZIN-3YL-THIOMETHYL SUBSTITUTED DERIVATIVES OF CEPHALOSPORIN</title><date>1983-06-20</date><risdate>1983</risdate><abstract>Novel cephalosporins of the general formula are obtained by reaction of a 3-acetoxymethylcephalosporin of the formula with a triazinylthio derivative of the formula The substituents are defined in Claim 1. If necessary, the amino and/or carboxyl groups are intermediately protected and, if it is desired, the compounds obtained according to the invention are acylated by the known processes. The reaction is preferably carried out in polar solvents, e.g. water. These novel cephalosporins are to be used on the one hand as medicines having antibiotic activity or on the other hand as intermediates in the preparation of antibiotics.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 5-OXO-6-HYDROXY-4,5-DIHYDRO-1,2,5-TRIAZIN-3YL-THIOMETHYL SUBSTITUTED DERIVATIVES OF CEPHALOSPORIN |
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