NITROGENATED HETEROCYCLIC AMIDE COMPOUND, AND USE THEREOF FOR MEDICAL PURPOSES
The present invention provides a compound which has a PDHK-inhibiting activity and is useful for the treatment or prevention of diabetes (type 1 diabetes, type 2 diabetes, etc.), insulin resistance syndrome, metabolic syndrome, hyperglycemia, hyperlactatemia, diabetes complications (diabetic neuropa...
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| creator | MAEBA, Takaki SUZAWA, Koichi KOTOKU, Masayuki YAMAOKA, Nobutaka MOTODA, Dai MASUO, Ritsuki |
| description | The present invention provides a compound which has a PDHK-inhibiting activity and is useful for the treatment or prevention of diabetes (type 1 diabetes, type 2 diabetes, etc.), insulin resistance syndrome, metabolic syndrome, hyperglycemia, hyperlactatemia, diabetes complications (diabetic neuropathy, diabetic retinopathy, diabetic nephropathy, cataract, etc.), heart failure (acute heart failure, chronic heart failure), cardiomyopathy, myocardial ischemia, myocardial infarction, angina pectoris, dyslipidemia, atherosclerosis, peripheral arterial disease, intermittent claudication, chronic obstructive pulmonary disease, brain ischemia, stroke, mitochondrial disease, mitochondrial encephalomyopathy, cancer, pulmonary hypertension or Alzheimer's disease. The present invention relates to a compound represented by formula [I-a] or [II] or a pharmaceutically acceptable salt thereof. [In the formulae, each symbol is as defined in the description.] |
| format | Patent |
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The present invention relates to a compound represented by formula [I-a] or [II] or a pharmaceutically acceptable salt thereof. 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The present invention relates to a compound represented by formula [I-a] or [II] or a pharmaceutically acceptable salt thereof. 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The present invention relates to a compound represented by formula [I-a] or [II] or a pharmaceutically acceptable salt thereof. [In the formulae, each symbol is as defined in the description.]</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NITROGENATED HETEROCYCLIC AMIDE COMPOUND, AND USE THEREOF FOR MEDICAL PURPOSES |
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