LIVE VIRUS HAVING A BANK OF DENGUE VIRUS ATTENUATED STRAINS, AND A DENGUE VACCINE CONTAINING SAME AS ANTIGENS

A highly safe dengue vaccine was invented that induced a neutralizing antibody response against all of the four serotypes of dengue virus without developing more than a fixed level of viremia with single administration. A tetravalent dengue virus formulation is provided that is excellent in both eff...

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Hauptverfasser:	YAMAORI, Susumu, ABE, Motoharu, SHINMURA, Yasuhiko, TAKAGI, Shota, MARUNO, Shinichi, HAYASHI, Yasuhisa, UCHIDA, Naomi, SONODA, Kengo, KOMURA, Fusae, FUKUDA, Aki, KAMEYAMA, Kazuhisa, YOSHIMURA, Masaya
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A highly safe dengue vaccine was invented that induced a neutralizing antibody response against all of the four serotypes of dengue virus without developing more than a fixed level of viremia with single administration. A tetravalent dengue virus formulation is provided that is excellent in both efficacy (neutralizing antibody response) and safety (viremia).