FUSION MOLECULES

The present invention relates to fusion molecules that have binding specificity for pyoverdine type I, II and III and pyochelin and can be used in various applications, including diagnostic and/or therapeutic applications, for example, to inhibit or reduce growth of P. aeruginosa and/or to prevent o...

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Hauptverfasser: JENSEN, Kristian, RASSER, Hans-Falk, STUEDEMANN, Thomas, ALLERSDORFER, Andrea, LUNDE, Bradley, KRUIP, Jochen, RAT, Dorothea, REY, Astrid, LANGE, Christian, SCHAEFER, Juergen, FRAISSE, Laurent, HINNER, Marlon, STUMP, Heike, WIEDENMANN, Alexander, CALANDRA, Bernhard, HULSMEYER, Martin, CORVEY, Carsten, FOCKEN, Ingo, MOUREZ, Michael, ROTHE, Christine
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creator JENSEN, Kristian
RASSER, Hans-Falk
STUEDEMANN, Thomas
ALLERSDORFER, Andrea
LUNDE, Bradley
KRUIP, Jochen
RAT, Dorothea
REY, Astrid
LANGE, Christian
SCHAEFER, Juergen
FRAISSE, Laurent
HINNER, Marlon
STUMP, Heike
WIEDENMANN, Alexander
CALANDRA, Bernhard
HULSMEYER, Martin
CORVEY, Carsten
FOCKEN, Ingo
MOUREZ, Michael
ROTHE, Christine
description The present invention relates to fusion molecules that have binding specificity for pyoverdine type I, II and III and pyochelin and can be used in various applications, including diagnostic and/or therapeutic applications, for example, to inhibit or reduce growth of P. aeruginosa and/or to prevent or treat P. aeruginosa biofilm infection as well as diseases or disorders associated with P. aeruginosa biofilm infection. The present invention also concerns methods of producing the fusion molecules described herein as well as compositions and kits comprising such fusion molecules. The present invention further relates to nucleic acid molecules encoding the fusion molecules described herein.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title FUSION MOLECULES
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