THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE
Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, an...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | CHEUNG, Eugene Y SANTILLAN, Alejandro WIENER, John J. M BROGGINI, Diego CHROVIAN, Christa C DENG, Xiaohu BACANI, Genesis M LEE-DUTRA, Alice GOMEZ, Laurent SAPPEY, Kathleen C SEPASSI, Kia WICKBOLDT, Alvah T FOURINE, Anne M GRICE, Cheryl A KEARNEY, Aaron M LANDRY-BAYLE, Adrianne M MANI, Neelakandha S LOCHNER, Susanne TANIS, Virginia M ZINSER, Hartmut LIANG, Jimmy T |
| description | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_PH12013500094B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>PH12013500094B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_PH12013500094B13</originalsourceid><addsrcrecordid>eNqNyrsKwjAUANAuDqL-wx1cA-nDwfFqUhJMc0uSgulSisRJtFj_HxcHBwens5xl9gxKY0-G2ui00JYVLBo6R9YqaaMBtAK-CvY_SqOt9IAeGhKdwUDOA9VgZHei4LS0ErACFYUjg16us8V1vM1p83GVbWsZjoql6TGkeRov6Z5eQ6vygufljnO-rw55-Wd7Ax0UOkk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE</title><source>esp@cenet</source><creator>CHEUNG, Eugene Y ; SANTILLAN, Alejandro ; WIENER, John J. M ; BROGGINI, Diego ; CHROVIAN, Christa C ; DENG, Xiaohu ; BACANI, Genesis M ; LEE-DUTRA, Alice ; GOMEZ, Laurent ; SAPPEY, Kathleen C ; SEPASSI, Kia ; WICKBOLDT, Alvah T ; FOURINE, Anne M ; GRICE, Cheryl A ; KEARNEY, Aaron M ; LANDRY-BAYLE, Adrianne M ; MANI, Neelakandha S ; LOCHNER, Susanne ; TANIS, Virginia M ; ZINSER, Hartmut ; LIANG, Jimmy T</creator><creatorcontrib>CHEUNG, Eugene Y ; SANTILLAN, Alejandro ; WIENER, John J. M ; BROGGINI, Diego ; CHROVIAN, Christa C ; DENG, Xiaohu ; BACANI, Genesis M ; LEE-DUTRA, Alice ; GOMEZ, Laurent ; SAPPEY, Kathleen C ; SEPASSI, Kia ; WICKBOLDT, Alvah T ; FOURINE, Anne M ; GRICE, Cheryl A ; KEARNEY, Aaron M ; LANDRY-BAYLE, Adrianne M ; MANI, Neelakandha S ; LOCHNER, Susanne ; TANIS, Virginia M ; ZINSER, Hartmut ; LIANG, Jimmy T</creatorcontrib><description>Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150223&DB=EPODOC&CC=PH&NR=12013500094B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150223&DB=EPODOC&CC=PH&NR=12013500094B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEUNG, Eugene Y</creatorcontrib><creatorcontrib>SANTILLAN, Alejandro</creatorcontrib><creatorcontrib>WIENER, John J. M</creatorcontrib><creatorcontrib>BROGGINI, Diego</creatorcontrib><creatorcontrib>CHROVIAN, Christa C</creatorcontrib><creatorcontrib>DENG, Xiaohu</creatorcontrib><creatorcontrib>BACANI, Genesis M</creatorcontrib><creatorcontrib>LEE-DUTRA, Alice</creatorcontrib><creatorcontrib>GOMEZ, Laurent</creatorcontrib><creatorcontrib>SAPPEY, Kathleen C</creatorcontrib><creatorcontrib>SEPASSI, Kia</creatorcontrib><creatorcontrib>WICKBOLDT, Alvah T</creatorcontrib><creatorcontrib>FOURINE, Anne M</creatorcontrib><creatorcontrib>GRICE, Cheryl A</creatorcontrib><creatorcontrib>KEARNEY, Aaron M</creatorcontrib><creatorcontrib>LANDRY-BAYLE, Adrianne M</creatorcontrib><creatorcontrib>MANI, Neelakandha S</creatorcontrib><creatorcontrib>LOCHNER, Susanne</creatorcontrib><creatorcontrib>TANIS, Virginia M</creatorcontrib><creatorcontrib>ZINSER, Hartmut</creatorcontrib><creatorcontrib>LIANG, Jimmy T</creatorcontrib><title>THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE</title><description>Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrsKwjAUANAuDqL-wx1cA-nDwfFqUhJMc0uSgulSisRJtFj_HxcHBwens5xl9gxKY0-G2ui00JYVLBo6R9YqaaMBtAK-CvY_SqOt9IAeGhKdwUDOA9VgZHei4LS0ErACFYUjg16us8V1vM1p83GVbWsZjoql6TGkeRov6Z5eQ6vygufljnO-rw55-Wd7Ax0UOkk</recordid><startdate>20150223</startdate><enddate>20150223</enddate><creator>CHEUNG, Eugene Y</creator><creator>SANTILLAN, Alejandro</creator><creator>WIENER, John J. M</creator><creator>BROGGINI, Diego</creator><creator>CHROVIAN, Christa C</creator><creator>DENG, Xiaohu</creator><creator>BACANI, Genesis M</creator><creator>LEE-DUTRA, Alice</creator><creator>GOMEZ, Laurent</creator><creator>SAPPEY, Kathleen C</creator><creator>SEPASSI, Kia</creator><creator>WICKBOLDT, Alvah T</creator><creator>FOURINE, Anne M</creator><creator>GRICE, Cheryl A</creator><creator>KEARNEY, Aaron M</creator><creator>LANDRY-BAYLE, Adrianne M</creator><creator>MANI, Neelakandha S</creator><creator>LOCHNER, Susanne</creator><creator>TANIS, Virginia M</creator><creator>ZINSER, Hartmut</creator><creator>LIANG, Jimmy T</creator><scope>EVB</scope></search><sort><creationdate>20150223</creationdate><title>THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE</title><author>CHEUNG, Eugene Y ; SANTILLAN, Alejandro ; WIENER, John J. M ; BROGGINI, Diego ; CHROVIAN, Christa C ; DENG, Xiaohu ; BACANI, Genesis M ; LEE-DUTRA, Alice ; GOMEZ, Laurent ; SAPPEY, Kathleen C ; SEPASSI, Kia ; WICKBOLDT, Alvah T ; FOURINE, Anne M ; GRICE, Cheryl A ; KEARNEY, Aaron M ; LANDRY-BAYLE, Adrianne M ; MANI, Neelakandha S ; LOCHNER, Susanne ; TANIS, Virginia M ; ZINSER, Hartmut ; LIANG, Jimmy T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PH12013500094B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2015</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEUNG, Eugene Y</creatorcontrib><creatorcontrib>SANTILLAN, Alejandro</creatorcontrib><creatorcontrib>WIENER, John J. M</creatorcontrib><creatorcontrib>BROGGINI, Diego</creatorcontrib><creatorcontrib>CHROVIAN, Christa C</creatorcontrib><creatorcontrib>DENG, Xiaohu</creatorcontrib><creatorcontrib>BACANI, Genesis M</creatorcontrib><creatorcontrib>LEE-DUTRA, Alice</creatorcontrib><creatorcontrib>GOMEZ, Laurent</creatorcontrib><creatorcontrib>SAPPEY, Kathleen C</creatorcontrib><creatorcontrib>SEPASSI, Kia</creatorcontrib><creatorcontrib>WICKBOLDT, Alvah T</creatorcontrib><creatorcontrib>FOURINE, Anne M</creatorcontrib><creatorcontrib>GRICE, Cheryl A</creatorcontrib><creatorcontrib>KEARNEY, Aaron M</creatorcontrib><creatorcontrib>LANDRY-BAYLE, Adrianne M</creatorcontrib><creatorcontrib>MANI, Neelakandha S</creatorcontrib><creatorcontrib>LOCHNER, Susanne</creatorcontrib><creatorcontrib>TANIS, Virginia M</creatorcontrib><creatorcontrib>ZINSER, Hartmut</creatorcontrib><creatorcontrib>LIANG, Jimmy T</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEUNG, Eugene Y</au><au>SANTILLAN, Alejandro</au><au>WIENER, John J. M</au><au>BROGGINI, Diego</au><au>CHROVIAN, Christa C</au><au>DENG, Xiaohu</au><au>BACANI, Genesis M</au><au>LEE-DUTRA, Alice</au><au>GOMEZ, Laurent</au><au>SAPPEY, Kathleen C</au><au>SEPASSI, Kia</au><au>WICKBOLDT, Alvah T</au><au>FOURINE, Anne M</au><au>GRICE, Cheryl A</au><au>KEARNEY, Aaron M</au><au>LANDRY-BAYLE, Adrianne M</au><au>MANI, Neelakandha S</au><au>LOCHNER, Susanne</au><au>TANIS, Virginia M</au><au>ZINSER, Hartmut</au><au>LIANG, Jimmy T</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE</title><date>2015-02-23</date><risdate>2015</risdate><abstract>Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_PH12013500094B1 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | THIAZOLOPYRIDIN-2-YLOXY-PHENYL AND THIAZOLOPYRAZIN-2-YLOXY-PHENYL AMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T16%3A47%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CHEUNG,%20Eugene%20Y&rft.date=2015-02-23&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EPH12013500094B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |