FORMA CRISTALINA DE N-[4-[4-(4-MORFOLINIL)-7H-PIRROLO[2,3-D]PIRIMIDIN-6-IL]FENIL]-4-[[3(R)- [(1-OXO)-2-PROPEN-1-IL)AMINO]-1-PIPERIDINIL]METIL]-2-PIRIDINACARBOXAMIDA, UN INHIBIDOR IRREVERSIBLE DE MENINA-MLL PARA EL TRATAMIENTO DEL CANCER

Se refiere a una forma cristalina D de N-[4-[4-(4-morfolinil)-7H-pirrolo[2,3-d]pirimidin-6-il]fenil]-4-[[3(R)-[ (1-oxo-2-propen-1-il)amino]-1-piperidinil]metil]-2-piridincarboxamida (Compuesto A) de Formula I, en la que la Forma cristalina D se caracteriza por un patron de difraccion de rayos X en p...

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Hauptverfasser:	KINOSHITA, Taisei, BUTLER, Thomas, PALMER, James T, JIANG, Siyi, TAN, Heow, LAW, Brian, SOMANATH, Priyanka, WONG, Angelina Sau Man, HE, Hongyan, LU, Daniel, LIN, Nan-Horng
Format:	Patent
Sprache:	spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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