NUEVOS INMUNOCONJUGADOS DE INTERLEUCINA-7
La presente invencion se refiere a polipeptidos de interleucina-7 mutante, inmunoconjugados, particularmente inmunoconjugados que comprenden un polipeptido de interleucina-7 mutante y un anticuerpo que se une a PD-1. Ademas, la invencion se refiere a moleculas de polinucleotidos que codifican los po...
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| creator | FREIMOSER-GRUNDSCHOBER, Anne CODARRI DEAK, Laura KOLL, Johann UMANA, Pablo KLEIN, Christian CARPY GUTIERREZ CIRLOS, Alejandro MOESSNER, Ekkehard NICOLINI, Valeria LAUENER, Laura DURINI, Greta SCHULENBURG, Cindy |
| description | La presente invencion se refiere a polipeptidos de interleucina-7 mutante, inmunoconjugados, particularmente inmunoconjugados que comprenden un polipeptido de interleucina-7 mutante y un anticuerpo que se une a PD-1. Ademas, la invencion se refiere a moleculas de polinucleotidos que codifican los polipeptidos de interleucina-7 mutante o los inmunoconjugados, y vectores y celulas huesped que comprenden tales moleculas de polinucleotidos. La invencion se refiere ademas a metodos para producir los polipeptidos de interleucina-7 mutante, inmunoconjugados, composiciones farmaceuticas que los comprenden, y usos de estos para el tratamiento del cancer.
Provided are mutant interleukin-7 polypeptides, immunoconjugates, particularly immunoconjugates comprising a mutant interleukin-7 polypeptide and an antibody that binds to PD-1. In addition, provided are polynucleotide molecules encoding the mutant interleukin-7 polypeptides or the immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. Also provided are methods for producing the mutant interleukin-7 polypeptides, immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof. |
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Provided are mutant interleukin-7 polypeptides, immunoconjugates, particularly immunoconjugates comprising a mutant interleukin-7 polypeptide and an antibody that binds to PD-1. In addition, provided are polynucleotide molecules encoding the mutant interleukin-7 polypeptides or the immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. Also provided are methods for producing the mutant interleukin-7 polypeptides, immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof.</description><language>spa</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240807&DB=EPODOC&CC=PE&NR=20241627A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240807&DB=EPODOC&CC=PE&NR=20241627A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FREIMOSER-GRUNDSCHOBER, Anne</creatorcontrib><creatorcontrib>CODARRI DEAK, Laura</creatorcontrib><creatorcontrib>KOLL, Johann</creatorcontrib><creatorcontrib>UMANA, Pablo</creatorcontrib><creatorcontrib>KLEIN, Christian</creatorcontrib><creatorcontrib>CARPY GUTIERREZ CIRLOS, Alejandro</creatorcontrib><creatorcontrib>MOESSNER, Ekkehard</creatorcontrib><creatorcontrib>NICOLINI, Valeria</creatorcontrib><creatorcontrib>LAUENER, Laura</creatorcontrib><creatorcontrib>DURINI, Greta</creatorcontrib><creatorcontrib>SCHULENBURG, Cindy</creatorcontrib><title>NUEVOS INMUNOCONJUGADOS DE INTERLEUCINA-7</title><description>La presente invencion se refiere a polipeptidos de interleucina-7 mutante, inmunoconjugados, particularmente inmunoconjugados que comprenden un polipeptido de interleucina-7 mutante y un anticuerpo que se une a PD-1. Ademas, la invencion se refiere a moleculas de polinucleotidos que codifican los polipeptidos de interleucina-7 mutante o los inmunoconjugados, y vectores y celulas huesped que comprenden tales moleculas de polinucleotidos. La invencion se refiere ademas a metodos para producir los polipeptidos de interleucina-7 mutante, inmunoconjugados, composiciones farmaceuticas que los comprenden, y usos de estos para el tratamiento del cancer.
Provided are mutant interleukin-7 polypeptides, immunoconjugates, particularly immunoconjugates comprising a mutant interleukin-7 polypeptide and an antibody that binds to PD-1. In addition, provided are polynucleotide molecules encoding the mutant interleukin-7 polypeptides or the immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. Also provided are methods for producing the mutant interleukin-7 polypeptides, immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND0C3UN8w9W8PTzDfXzd_b38wp1d3QBCri4AsVCXIN8XEOdPf0cdc15GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakl8gKuRgZGJoZmRuaOhMTFqAENHJH0</recordid><startdate>20240807</startdate><enddate>20240807</enddate><creator>FREIMOSER-GRUNDSCHOBER, Anne</creator><creator>CODARRI DEAK, Laura</creator><creator>KOLL, Johann</creator><creator>UMANA, Pablo</creator><creator>KLEIN, Christian</creator><creator>CARPY GUTIERREZ CIRLOS, Alejandro</creator><creator>MOESSNER, Ekkehard</creator><creator>NICOLINI, Valeria</creator><creator>LAUENER, Laura</creator><creator>DURINI, Greta</creator><creator>SCHULENBURG, Cindy</creator><scope>EVB</scope></search><sort><creationdate>20240807</creationdate><title>NUEVOS INMUNOCONJUGADOS DE INTERLEUCINA-7</title><author>FREIMOSER-GRUNDSCHOBER, Anne ; CODARRI DEAK, Laura ; KOLL, Johann ; UMANA, Pablo ; KLEIN, Christian ; CARPY GUTIERREZ CIRLOS, Alejandro ; MOESSNER, Ekkehard ; NICOLINI, Valeria ; LAUENER, Laura ; DURINI, Greta ; SCHULENBURG, Cindy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PE20241627A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>FREIMOSER-GRUNDSCHOBER, Anne</creatorcontrib><creatorcontrib>CODARRI DEAK, Laura</creatorcontrib><creatorcontrib>KOLL, Johann</creatorcontrib><creatorcontrib>UMANA, Pablo</creatorcontrib><creatorcontrib>KLEIN, Christian</creatorcontrib><creatorcontrib>CARPY GUTIERREZ CIRLOS, Alejandro</creatorcontrib><creatorcontrib>MOESSNER, Ekkehard</creatorcontrib><creatorcontrib>NICOLINI, Valeria</creatorcontrib><creatorcontrib>LAUENER, Laura</creatorcontrib><creatorcontrib>DURINI, Greta</creatorcontrib><creatorcontrib>SCHULENBURG, Cindy</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FREIMOSER-GRUNDSCHOBER, Anne</au><au>CODARRI DEAK, Laura</au><au>KOLL, Johann</au><au>UMANA, Pablo</au><au>KLEIN, Christian</au><au>CARPY GUTIERREZ CIRLOS, Alejandro</au><au>MOESSNER, Ekkehard</au><au>NICOLINI, Valeria</au><au>LAUENER, Laura</au><au>DURINI, Greta</au><au>SCHULENBURG, Cindy</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NUEVOS INMUNOCONJUGADOS DE INTERLEUCINA-7</title><date>2024-08-07</date><risdate>2024</risdate><abstract>La presente invencion se refiere a polipeptidos de interleucina-7 mutante, inmunoconjugados, particularmente inmunoconjugados que comprenden un polipeptido de interleucina-7 mutante y un anticuerpo que se une a PD-1. Ademas, la invencion se refiere a moleculas de polinucleotidos que codifican los polipeptidos de interleucina-7 mutante o los inmunoconjugados, y vectores y celulas huesped que comprenden tales moleculas de polinucleotidos. La invencion se refiere ademas a metodos para producir los polipeptidos de interleucina-7 mutante, inmunoconjugados, composiciones farmaceuticas que los comprenden, y usos de estos para el tratamiento del cancer.
Provided are mutant interleukin-7 polypeptides, immunoconjugates, particularly immunoconjugates comprising a mutant interleukin-7 polypeptide and an antibody that binds to PD-1. In addition, provided are polynucleotide molecules encoding the mutant interleukin-7 polypeptides or the immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. Also provided are methods for producing the mutant interleukin-7 polypeptides, immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | NUEVOS INMUNOCONJUGADOS DE INTERLEUCINA-7 |
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