DERIVADOS DE TETRAHIDROTIENO PIRIDINA COMO INHIBIDORES DE DDR
La presente invencion se refiere al desarrollo del compuesto de formula (I), que inhibe los Receptores de Dominio Discoidina (inhibidores de DDR), tambien, se refiere a metodos para preparar tales compuestos, composiciones farmaceuticas que los contienen y su uso terapeutico. Los compuestos de la in...
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creator | RIZZI, Andrea MULLINS, Toby Matthew Grover KARAWAJCZYK, Anna CLARK, David Edward KNIGHT, Keith Christopher WHITTAKER, Ben Paul WOLEK, Barbara Karolina RANCATI, Fabio IOTTI, Nicolò CARZANIGA, Laura LEVANTO, Stefano |
description | La presente invencion se refiere al desarrollo del compuesto de formula (I), que inhibe los Receptores de Dominio Discoidina (inhibidores de DDR), tambien, se refiere a metodos para preparar tales compuestos, composiciones farmaceuticas que los contienen y su uso terapeutico. Los compuestos de la invencion pueden ser utiles, por ejemplo, en el tratamiento de varios trastornos asociados a los mecanismos de DDR.
The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms. |
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The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.</description><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240227&DB=EPODOC&CC=PE&NR=20240358A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240227&DB=EPODOC&CC=PE&NR=20240358A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RIZZI, Andrea</creatorcontrib><creatorcontrib>MULLINS, Toby Matthew Grover</creatorcontrib><creatorcontrib>KARAWAJCZYK, Anna</creatorcontrib><creatorcontrib>CLARK, David Edward</creatorcontrib><creatorcontrib>KNIGHT, Keith Christopher</creatorcontrib><creatorcontrib>WHITTAKER, Ben Paul</creatorcontrib><creatorcontrib>WOLEK, Barbara Karolina</creatorcontrib><creatorcontrib>RANCATI, Fabio</creatorcontrib><creatorcontrib>IOTTI, Nicolò</creatorcontrib><creatorcontrib>CARZANIGA, Laura</creatorcontrib><creatorcontrib>LEVANTO, Stefano</creatorcontrib><title>DERIVADOS DE TETRAHIDROTIENO PIRIDINA COMO INHIBIDORES DE DDR</title><description>La presente invencion se refiere al desarrollo del compuesto de formula (I), que inhibe los Receptores de Dominio Discoidina (inhibidores de DDR), tambien, se refiere a metodos para preparar tales compuestos, composiciones farmaceuticas que los contienen y su uso terapeutico. Los compuestos de la invencion pueden ser utiles, por ejemplo, en el tratamiento de varios trastornos asociados a los mecanismos de DDR.
The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB1cQ3yDHN08Q9WcHFVCHENCXL08HQJ8g_xdPXzVwjwDPJ08fRzVHD29_VX8PTz8HTydPEPcgUrdnEJ4mFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8QGuRgZGJgbGphaOhsbEqAEAJp0prg</recordid><startdate>20240227</startdate><enddate>20240227</enddate><creator>RIZZI, Andrea</creator><creator>MULLINS, Toby Matthew Grover</creator><creator>KARAWAJCZYK, Anna</creator><creator>CLARK, David Edward</creator><creator>KNIGHT, Keith Christopher</creator><creator>WHITTAKER, Ben Paul</creator><creator>WOLEK, Barbara Karolina</creator><creator>RANCATI, Fabio</creator><creator>IOTTI, Nicolò</creator><creator>CARZANIGA, Laura</creator><creator>LEVANTO, Stefano</creator><scope>EVB</scope></search><sort><creationdate>20240227</creationdate><title>DERIVADOS DE TETRAHIDROTIENO PIRIDINA COMO INHIBIDORES DE DDR</title><author>RIZZI, Andrea ; MULLINS, Toby Matthew Grover ; KARAWAJCZYK, Anna ; CLARK, David Edward ; KNIGHT, Keith Christopher ; WHITTAKER, Ben Paul ; WOLEK, Barbara Karolina ; RANCATI, Fabio ; IOTTI, Nicolò ; CARZANIGA, Laura ; LEVANTO, Stefano</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PE20240358A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>RIZZI, Andrea</creatorcontrib><creatorcontrib>MULLINS, Toby Matthew Grover</creatorcontrib><creatorcontrib>KARAWAJCZYK, Anna</creatorcontrib><creatorcontrib>CLARK, David Edward</creatorcontrib><creatorcontrib>KNIGHT, Keith Christopher</creatorcontrib><creatorcontrib>WHITTAKER, Ben Paul</creatorcontrib><creatorcontrib>WOLEK, Barbara Karolina</creatorcontrib><creatorcontrib>RANCATI, Fabio</creatorcontrib><creatorcontrib>IOTTI, Nicolò</creatorcontrib><creatorcontrib>CARZANIGA, Laura</creatorcontrib><creatorcontrib>LEVANTO, Stefano</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RIZZI, Andrea</au><au>MULLINS, Toby Matthew Grover</au><au>KARAWAJCZYK, Anna</au><au>CLARK, David Edward</au><au>KNIGHT, Keith Christopher</au><au>WHITTAKER, Ben Paul</au><au>WOLEK, Barbara Karolina</au><au>RANCATI, Fabio</au><au>IOTTI, Nicolò</au><au>CARZANIGA, Laura</au><au>LEVANTO, Stefano</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVADOS DE TETRAHIDROTIENO PIRIDINA COMO INHIBIDORES DE DDR</title><date>2024-02-27</date><risdate>2024</risdate><abstract>La presente invencion se refiere al desarrollo del compuesto de formula (I), que inhibe los Receptores de Dominio Discoidina (inhibidores de DDR), tambien, se refiere a metodos para preparar tales compuestos, composiciones farmaceuticas que los contienen y su uso terapeutico. Los compuestos de la invencion pueden ser utiles, por ejemplo, en el tratamiento de varios trastornos asociados a los mecanismos de DDR.
The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | DERIVADOS DE TETRAHIDROTIENO PIRIDINA COMO INHIBIDORES DE DDR |
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