DERIVADOS DE TETRAHIDROTIENO PIRIDINA COMO INHIBIDORES DE DDR

La presente invencion se refiere al desarrollo del compuesto de formula (I), que inhibe los Receptores de Dominio Discoidina (inhibidores de DDR), tambien, se refiere a metodos para preparar tales compuestos, composiciones farmaceuticas que los contienen y su uso terapeutico. Los compuestos de la in...

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Hauptverfasser: RIZZI, Andrea, MULLINS, Toby Matthew Grover, KARAWAJCZYK, Anna, CLARK, David Edward, KNIGHT, Keith Christopher, WHITTAKER, Ben Paul, WOLEK, Barbara Karolina, RANCATI, Fabio, IOTTI, Nicolò, CARZANIGA, Laura, LEVANTO, Stefano
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creator RIZZI, Andrea
MULLINS, Toby Matthew Grover
KARAWAJCZYK, Anna
CLARK, David Edward
KNIGHT, Keith Christopher
WHITTAKER, Ben Paul
WOLEK, Barbara Karolina
RANCATI, Fabio
IOTTI, Nicolò
CARZANIGA, Laura
LEVANTO, Stefano
description La presente invencion se refiere al desarrollo del compuesto de formula (I), que inhibe los Receptores de Dominio Discoidina (inhibidores de DDR), tambien, se refiere a metodos para preparar tales compuestos, composiciones farmaceuticas que los contienen y su uso terapeutico. Los compuestos de la invencion pueden ser utiles, por ejemplo, en el tratamiento de varios trastornos asociados a los mecanismos de DDR. The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DERIVADOS DE TETRAHIDROTIENO PIRIDINA COMO INHIBIDORES DE DDR
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